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ROS-Responsive Hydrogel-Delivered miR-665 Targets STAT3 to Alleviate Inflammation and Promote Hair Follicle Regeneration in Alopecia Areata

research ROS-Responsive Hydrogel-Delivered miR-665 Targets STAT3 to Alleviate Inflammation and Promote Hair Follicle Regeneration in Alopecia Areata

February 2026 in “Journal of Nanobiotechnology”

A new treatment using a special gel with miR-665 reduces inflammation and helps hair regrow in alopecia areata.

Programmed Nanozyme Hydrogel Enabling Spatiotemporal Modulation of Wound Healing Achieves Skin Regeneration After Biofilm Infection

research Programmed Nanozyme Hydrogel Enabling Spatiotemporal Modulation of Wound Healing Achieves Skin Regeneration After Biofilm Infection

October 2025 in “Journal of Nanobiotechnology”

The hydrogel helps wounds heal better by reducing inflammation and promoting skin regeneration.

research Responsive Microneedles as a New Platform for Precision Immunotherapy

17 citations , May 2023 in “Pharmaceutics”

Microneedles can precisely deliver cancer treatments with fewer side effects.

research Biomembrane-Based Nanostructure and Microstructure Loaded Hydrogels for Promoting Chronic Wound Healing

24 citations , January 2023 in “International Journal of Nanomedicine”

Biomembrane-based hydrogels can effectively promote chronic wound healing.

research Advances in Research of Hydrogel Microneedle-Based Delivery Systems for Disease Treatment

14 citations , December 2024 in “Pharmaceutics”

Hydrogel microneedles offer a promising, minimally invasive way to treat diseases like cancer and hair loss, but need improvements in strength and standardization.

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Community Join

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 124 upvotes 1 year ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 486 upvotes 1 year ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 736 upvotes 3 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Hypoxia (lack of oxygen) enhances hair growth via stem cells

in Treatment 45 upvotes 1 year ago

Hypoxia may enhance hair growth by stimulating stem cells, but it could also risk fibrosis. Some users humorously discuss extreme methods like choking while using minoxidil, highlighting the need for new treatments.

community Possible topical option for preventing BDNF-related hair loss

in Research/Science 7 upvotes 2 years ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

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