24 citations
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September 2005 in “Journal of Cellular Biochemistry”
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.
Low testosterone and estradiol may contribute to hair loss, and blocking DHT without sufficient hormone levels might hinder regrowth. The discussion highlights the importance of hormone balance, with some considering supplements and lifestyle changes to support hair health.
People often stop posting about hair loss after seeing success with treatments. The user used oral and topical minoxidil, finasteride, and microneedling.
Some people may not respond to topical minoxidil due to low SULT1A1 enzyme activity, but oral minoxidil can be effective. Tretinoin may enhance minoxidil's effectiveness, and some users prefer oral minoxidil despite side effects.
The post discusses the rarity of baldness among South Korean men. Users suggest this could be due to early treatment, high beauty standards, accessibility of healthcare, and genetics. Treatments like finasteride and dutasteride are commonly used, and hair transplants are also popular.