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GlossaryChloracne

rare skin condition caused by exposure to toxic chemicals

Chloracne is a rare skin condition resembling severe acne, caused by exposure to certain toxic chemicals, particularly chlorinated compounds like dioxins. It manifests as blackheads, cysts, and pustules, primarily on the face, neck, and upper body, and is often associated with occupational or environmental exposure to these harmful substances.

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research Activation of Nrf2 in Keratinocytes Causes Chloracne-Like Skin Disease in Mice

81 citations, February 2014 in “EMBO molecular medicine”

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

research Chloracne: Histopathologic Findings in One Case

18 citations, April 2002 in “Journal of cutaneous pathology”

Tiny infundibular cysts are the main lesions in chloracne, not comedones.

research TCDD-Induced Activation of Aryl Hydrocarbon Receptor Regulates the Skin Stem Cell Population

9 citations, January 2015 in “Medical hypotheses”

TCDD disrupts skin stem cells, causing skin issues like chloracne.

2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

86 citations, August 2011 in “Toxicological sciences”

TCDD speeds up skin barrier formation by increasing certain gene expressions.

research Sorafenib-Associated Facial Acneiform Eruption

15 citations, December 2014 in “Dermatology and therapy”

Sorafenib can cause facial acne-like eruptions, which improve after reducing the dose or stopping the drug.

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community Hair Loss Due To Chlorine and Hard Metals In Water?

in Research/Science 1 upvotes 9 months ago

Hair loss possibly caused by chlorine and heavy metals in water was addressed by using a shower filter, ketoconazole shampoo, and PRP sessions, which stopped the hair loss but did not lead to regrowth. Other users suggested similar experiences and solutions, emphasizing the importance of a good water filter and patience for potential regrowth.

community Water hardness and hair looseness

10 upvotes 5 years ago

Hard water may contribute to hair loss. Using a showerhead filter improved hair retention and reduced hair fallout with white bulbs.

community Genuine Minoxidil Sanity Check-Tiktok Shops

in Minoxidil 187 upvotes 2 weeks ago

A user bought Kirkland Minoxidil from a TikTok shop and sought confirmation of its authenticity through a bleach test, which some users warned could be dangerous. Many participants advised against buying from TikTok due to the risk of fakes, suggesting alternatives like buying from Costco or reputable online pharmacies.

community Warning: Minoxidil usage around pets

in Minoxidil 454 upvotes 6 months ago

Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.

community Cold showers = healthier scalp?

in Chat 13 upvotes 1 year ago

Cold showers may improve scalp health for some, reducing itchiness and dandruff, but may increase dandruff for others while improving hair texture. Individual experiences with cold showers and scalp health vary.

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