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community Rapid Minoxidil Response Test (TrichoGene) - anyone tried it?

in Minoxidil 6 upvotes 1 year ago

A user tried the Rapid Minoxidil Response Test (TrichoGene) and found they don't respond to topical Minoxidil, so they added tretinoin. The test is available internationally, and another user is considering ordering it.

community High testosterone on 4 months dut, rapidly receding but no actually shed

in Finasteride/Dutasteride 21 upvotes 1 year ago

The user added 0.5mg dutasteride to their regimen of topical finasteride and minoxidil but experienced rapid hairline recession despite reduced hair fall. Suggestions included increasing the dutasteride dosage to 1mg daily to better suppress DHT and potentially adding oral minoxidil.

community DHT results after 1 year on dutasteride, confused and seeking guidance

in Finasteride/Dutasteride 107 upvotes 1 year ago

The user is experiencing rapid hair loss despite using dutasteride, finasteride, and minoxidil, and is concerned about high estradiol and testosterone levels. They are advised to consult an endocrinologist for potential hormonal imbalances.

community Hairloss has destroyed my Life completely

in Chat 339 upvotes 1 year ago

A young person is distressed about rapid hair loss despite using finasteride and recently starting oral minoxidil. Many suggest continuing treatment, considering dutasteride, and seeking therapy for mental health support.

community Blood Results (UPDATED) TOTAL T 1279 ng/dL- 2 Yrs on Fin / 1.5 Yrs on Dut

9 upvotes 1 year ago

The user has been using a hair loss treatment regimen including RU58841, minoxidil, and dutasteride, but still experiences hairline recession and fatigue despite high testosterone levels. They are considering adjusting their dutasteride dosage due to concerns about libido and energy levels.

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Research

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research Doppler laser imaging predicts response to topical minoxidil in the treatment of female pattern hair loss.

7 citations , July 2016 in “PubMed”

This study found that laser Doppler velocimetry can non-invasively predict topical minoxidil response by correlating scalp blood flow changes with sulfotransferase enzyme activity in women with pattern hair loss.

research Clinical utility and validity of minoxidil response testing in androgenetic alopecia

May 2015 in “Journal of The American Academy of Dermatology”

Minoxidil response testing helps predict hair growth success.

research Rapid Intravenous Administration of Corticotropin as a Test of Adrenocortical Insufficiency

17 citations , August 1967 in “JAMA”

In this study, a plasma-fluorescent corticoid test effectively differentiated patients with adrenal insufficiency from those with normal adrenal function based on their response to corticotropin.

research 555 Doppler laser imaging predicts response to topical minoxidil in the treatment of female pattern hair loss

April 2016 in “Journal of Investigative Dermatology”

This study found a perfect correlation between laser Doppler velocimetry measurements of scalp blood perfusion after minoxidil application and sulfotransferase enzyme activity in hair follicles, indicating a potential non-invasive test to predict minoxidil response in female pattern hair loss.

research Comprehensive analysis of minoxidil effectiveness for hair growth

June 2026 in “Journal of Comprehensive Dermatology”

This study reviewed the evidence on minoxidil's effectiveness for androgenetic alopecia, finding that 5% topical minoxidil is the most effective monotherapy for men, while 2% is similarly effective for women. Genetic markers can predict response, and new formulations like foam and gel improve tolerability.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

Minoxidil 2%, 5% and 10% which is better to use? In a randomized trial in men, 5% topical minoxidil produced more hair growth than 2%. There is no approved 10% product and no head-to-head trial showing it beats 5%; higher strengths mainly add irritation and systemic absorption. Approved strengths differ by sex, so check the label for your product.
Minoxidil: the application and its effects counted in months Expect initial shedding in the first month, with visible results typically by three to six months.
From hypertension to hair: the unexpected story of minoxidil Minoxidil was developed as an oral blood-pressure drug and approved as Loniten in 1979; unwanted hair growth in patients led to topical Rogaine, approved for men in 1988 and for women in 1991. Trials support topical minoxidil for pattern hair loss, while low-dose oral minoxidil is a prescription drug used off-label and needs medical supervision.

learn Nanoxidil

learn Latanoprost

Is latanoprost more effective for hair regrowth than minoxidil? No trial has compared latanoprost and minoxidil head to head. Minoxidil has large randomized trials and FDA approval for hair loss, while latanoprost's scalp evidence is a single 24-week pilot in 16 men, so the published evidence does not support latanoprost being the more effective option.

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Experts

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Hair Loss Specialist
Dr. Fernando Testi, MD
Benissa, Comunitat Valenciana, Spain

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Dr. Fernando Testi, MD