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research Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment

239 citations , December 2013 in “Scientific Reports”

In this study, researchers developed a microfluidics-based method for creating uniform, size-controlled stem cell spheroids that enhance osteogenic differentiation when encapsulated in alginate-RGD microgels.

research Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA)

157 citations , December 2015 in “Journal of the American Academy of Dermatology”

This case study reported significant but temporary hair regrowth and skin repigmentation in a patient with vitiligo and alopecia areata during treatment with oral ruxolitinib.

research Rapidly progressing mycosis fungoides presenting as follicular mucinosis

76 citations , October 2000 in “Journal of the American Academy of Dermatology”

This case report indicates that follicular mucinosis can be an early sign of rapidly progressing mycosis fungoides, particularly with the aggressive folliculotropic variant.

research Rapid nongenomic modulation by neurosteroids of dendritic spines in the hippocampus: Androgen, oestrogen and corticosteroid

33 citations , December 2017 in “Journal of neuroendocrinology”

This study describes molecular mechanisms explaining how sex and stress steroids rapidly modulate dendritic spine formation in hippocampal neurons, suggesting recovery-like effects under steroid-depleted conditions compared to intact conditions.

research Mammalian target of rapamycin complex 1 (mTORC1) may modulate the timing of anagen entry in mouse hair follicles

28 citations , November 2012 in “Experimental dermatology”

This study suggests that mTORC1 may play a role in regulating the timing of hair growth cycle phases, particularly the initiation of the anagen phase.

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Community Join

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community A Novel Synergistic Strategy for Hair Loss Prevention and Reversal: Rapamycin, Finasteride, and Minoxidil

40 upvotes 9 months ago

Rapamycin, finasteride, and minoxidil are discussed as a strategy for hair loss prevention and reversal. Pulsed dosing of rapamycin is suggested to avoid conflicting effects with minoxidil.

community Rapid Minoxidil Response Test (TrichoGene) - anyone tried it?

in Minoxidil 6 upvotes 1 year ago

A user tried the Rapid Minoxidil Response Test (TrichoGene) and found they don't respond to topical Minoxidil, so they added tretinoin. The test is available internationally, and another user is considering ordering it.

community Experiencing Rapid Norwood 3 to 7 Progression and Thinning Crown

in General 69 upvotes 1 year ago

The user is experiencing rapid hair loss, progressing from Norwood 3 to 7, with thinning at the crown and receding hairline. Suggested treatments include finasteride, minoxidil, ketoconazole shampoo, and CBD with MCT oil.

community Diffuse thinning help: noticing rapid texture change and hair fall.

15 upvotes 3 days ago

The user is experiencing hair thinning and increased hair fall after switching from finasteride to dutasteride and increasing their oral minoxidil dose. The consensus is that these changes likely caused shedding, and advice varies on whether to continue both medications or just dutasteride.

community Hyper responder turned rapid diffuser despite maximal therapy — looking for specialist recommendations

32 upvotes 4 months ago

Despite using treatments like Dutasteride, Minoxidil, RU58841, and GHK-Cu injections, the individual continues to experience aggressive hair thinning and is seeking a specialist for further help. Suggestions include trying finasteride, dermarolling, or another hair transplant.

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Learn

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learn Rapamycin

Immune-suppressing drug, also called sirolimus

What is rapamycin, and how is it being studied as a potential treatment for hair loss? Rapamycin is being studied for hair loss due to its effects on the mTOR pathway.
Does topical rapamycin actually help reactivate dormant hair follicles? No study in living people has shown that topical rapamycin reactivates hair follicles; the evidence is from mice and cultured follicles.
Is rapamycin safe for long-term use on the scalp, or should it be used in cycles? There is no published human trial of topical rapamycin on the scalp, so nobody knows whether long-term use is safe; the idea of cycling it comes from community practice and theory, not from any study or guideline, and rapamycin for hair loss is an off-label use of a prescription immunosuppressant.
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learn rapeseed oil

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