61 citations
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April 2014 in “Radiation Research” This study observed that topically applied RTA 408 reduced the severity of radiation-induced dermatitis in mice, with the highest dose significantly reducing and alleviating skin damage and associated inflammation.
57 citations
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January 2004 in “Journal of Radiation Research” This study found that zinc supplementation reduced the severity and delayed the onset of radiation-induced skin injury in rats, with the greatest protection observed at a dose of 10 mg/kg/day.
50 citations
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August 2021 in “Stem Cell Research & Therapy” This study reports that adipose-derived stem cells can protect against radiation-induced dermatitis in rats by reducing apoptosis through lowering Cathepsin F expression, suggesting a potential new therapeutic approach.
16 citations
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February 2019 in “Journal of Cellular and Molecular Medicine” This study established a rat model of radiation-induced dermatitis using 90 Gy irradiation, which may aid in exploring new treatments and understanding the pathology, particularly highlighting autophagy regulation as a potential therapeutic target.
1 citations
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September 2014 in “Neuro-Oncology” This study found that the prophylactic use of shiunko ointment may help prevent or reduce the severity of radiation-induced scalp dermatitis in patients undergoing radiotherapy for brain tumors.