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The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

research The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

90 citations , January 2003 in “The Journal of Urology”

This study found that finasteride significantly reduced VEGF expression and microvessel density in prostatic suburethral tissue, suggesting a mechanism for decreased bleeding in patients with benign prostatic hyperplasia.

Retraction of: Transurethral Resection of Prostate and Bleeding: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial to See the Efficacy of Short-Term Use of Finasteride and Dutasteride on Operative Blood Loss and Prostatic Microvessel Density

research Retraction of: Bansal and Arora. J Endourol. Epub ahead of print; DOI: 10.1089/end.2016.0696

March 2017 in “Journal of endourology”

The journal retracted an article due to inaccurate statistics and asked the authors to revise and resubmit it.

research Should Finasteride Be Routinely Given Preoperatively for TURP?

2 citations , July 2013 in “ISRN Urology (Print)”

This review found that finasteride may reduce bleeding during or after TURP procedures compared to placebo, although the overall results were varied, and no long-term complications were reported.

research Effects of Yiqi Huayu Chinese Medicine on the Expression of MMP-2/TIMP-2 in BPH Rats

January 2011 in “Zhonghua zhongyiyao xuekan”

This study found that Yiqi Huayu Chinese medicine may inhibit benign prostatic hyperplasia in rats by reducing MMP-2 levels and vessel renewal, with effects comparable to finasteride.

research Finasteride given pre-operation on decreasing bleeding during TURP and its possible mechanisms: a Meta-analysis

January 2011 in “Shandong yiyao”

This analysis concluded that preoperative finasteride significantly reduced blood loss during transurethral resection of the prostate by potentially decreasing the expression of VEGF and microvessel density.

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community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 3 years ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

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