research Estranys matins de febrer: Pauline Fondevila
This study observed that new trienone compounds consistently showed higher 5alpha-reductase inhibitory activity compared to corresponding dienones across various biological models.
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5 / 1000+ resultsresearch Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
This study reports that newly synthesized steroidal trienones exhibit higher 5α-reductase inhibitory activity than dienones in various biological models, suggesting potential use in treating androgen-dependent diseases.
research Postpartum alopecia
This study observed that thyroid and hormone treatments did not resolve postpartum alopecia in a small patient group, and most cases may naturally revert to normal.
research New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors.
This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.
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1 / 1000+ resultscommunity Intriguing Molecular Structures and Questions (DHT, Progesterone, Fin, etc)
The conversation discusses the molecular structures of compounds that reduce DHT levels, including finasteride and Ashwagandha. It explores the potential of using Ashwagandha topically as a 5a reductase inhibitor.
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