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research New Progesterone Esters as 5α-Reductase Inhibitors
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5-Alpha-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research 17-Oximino-5-Androsten-3β-yl Esters: Synthesis, Antiproliferative Activity, Acute Toxicity, and Effect on Serum Androgen Level
Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.
research In Vitro Assessment of Deodorant Ingredients and Malodor Inhibiting Potentials of Ascorbic Acid, Orlistat, and Mastic Gum
Ascorbic acid, orlistat, and mastic gum can effectively reduce sweat odor.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
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5 / 181 resultscommunity How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that
Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.
community Female on DHT blockers, need some advice.
A female experiencing hair loss while on testosterone replacement therapy is using oral Minoxidil, Spironolactone, and finasteride, but still losing hair. Suggestions include switching to dutasteride, using topical anti-androgens, and reducing Nizoral shampoo use to prevent scalp dryness.
community Don't give up! 9 months on Minoxidil
A trans man shared progress pictures showing significant hair regrowth after 9 months on oral Minoxidil and 1.5 years on finasteride. He encourages others to stick with their treatments despite initial setbacks.
community Nandrolone Replacement Therapy
A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.
community What happened to the ‘funding’ for broccoli research in treating hair loss?
Hair loss discussion includes broccoli sprouts treatment, Fluridil 7%, and sulforaphane, with mixed results. Finasteride, minoxidil, and RU58841 are preferred by some users.