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GlossaryProgenitor Cells (progenitor cell populations)

cells that can differentiate into specific cell types but are more limited than stem cells

Progenitor cells are a type of cell that has the capacity to differentiate into a specific type of cell but is more limited than a stem cell. Unlike stem cells, which can divide indefinitely and become any cell type, progenitor cells are already on the path to becoming a particular kind of cell and can only divide a limited number of times. They play a crucial role in tissue development and repair, including in the regeneration of hair follicles.

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Research

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research PNKP Is Required for Maintaining the Integrity of Progenitor Cell Populations in Adult Mice

3 citations , July 2021 in “Life science alliance”

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

research Basal Cell Carcinomas in Mice Arise from Hair Follicle Stem Cells and Multiple Epithelial Progenitor Populations

178 citations , April 2011 in “Journal of Clinical Investigation”

Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.

research Discovering New Progenitor Cell Populations Through Lineage Tracing and In Vivo Imaging

13 citations , February 2020 in “Cold Spring Harbor Perspectives in Biology”

New methods have helped find cells that create other cells in the body.

research Defining Compartmentalized Stem and Progenitor Populations With Distinct Cell Division Frequency in the Ocular Surface Epithelium

June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Stem and progenitor cells in the eye have different division rates and locations, affecting how they respond to injury.

research Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair

265 citations , July 2012 in “Cell”

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

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Community Join

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community My Theory Of Androgenic Alopecia

in Research/Science 19 upvotes 2 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community A Theory on Why Microneedling Works

172 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 676 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

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