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research Effects of Scalp Massage on Physiological and Psychological Indices

1 citations , January 2013 in “Journal of S C C J”

This study suggests that scalp massage may reduce stress, as indicated by decreased salivary cortisol and increased secretory immunoglobulin A, and improve comfort by reducing physical fatigue and negative emotions.

research The Safety of Testosterone Therapy in Women

11 citations , September 2012 in “Journal of obstetrics and gynaecology Canada”

This review examines the scientific evidence on the short-term safety of testosterone therapy for treating hypoactive sexual desire disorder in women, without presenting new clinical results.

research Transmasculine Hormone Therapy

6 citations , April 2019 in “Endocrinology and Metabolism Clinics of North America”

This study observed that testosterone therapy in transgender men enhances both physical and mental health, is safe in the short and middle term with proper follow-up, and highlights the need for endocrinologists to provide gender-affirming care despite its limited presence in medical education.

research ORIGINAL RESEARCH—ENDOCRINOLOGY: Comparison of the Steady‐State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men

38 citations , February 2005 in “The journal of sexual medicine”

This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.

research Testosterone Therapy in Women: A Literature Review of Clinical Indications, Dosing, Routes of Administration, and Safety

April 2026 in “Cureus”

This narrative review concludes that long-term randomized controlled trials are needed to establish clear guidelines for testosterone therapy in women, given the lack of FDA-approved formulations and the variable quality of current treatments.

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Community Join

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community New BBC article on Finasteride just dropped

in Chat 318 upvotes 1 year ago

Finasteride and minoxidil are discussed as hair loss treatments, with mixed opinions on side effects like sexual dysfunction and mood changes. Some users report positive results, while others express concerns about potential risks and insufficient information.

community Dutasteride is way more effective than Finasteride (Study)

in Research/Science 184 upvotes 1 year ago

Dutasteride is more effective than Finasteride for hair loss, with similar safety profiles. Individual responses vary, and factors like Minoxidil use and age differences may influence results.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 2 years ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Most Promising Future Hair Loss Treatments In 2026

83 upvotes 1 week ago

Promising hair loss treatments in 2026 include GT20029, a topical androgen receptor degrader, and VDPHL01, an extended-release oral minoxidil, both offering safer alternatives with fewer side effects. Other treatments like sublingual minoxidil, OND-1, JW0061, TDM-105795, and AMP-303 are also being explored.

community Do you believe these studies are real or just fear mongering

in Finasteride/Dutasteride 157 upvotes 11 months ago

Finasteride can regrow hair but may cause depression and suicidal thoughts in some users. The connection between finasteride and mental health issues is debated, with some attributing it to pre-existing conditions or stress.

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Experts

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Hair System Specialist
Hayley Short
Plymouth, England, United Kingdom

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Hayley Short