In preclinical studies, topical CUR61414 reduced Hh signaling and shrank BCCs in mice, but this study found no clinical efficacy in human superficial or nodular BCCs.
16 citations
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January 2012 in “Asian pacific Journal of Tropical Biomedicine” This study found that a 2% polyherbal phyto-complex cream containing aqueous extracts of Trichosanthes cucumerina and Abrus precatorius effectively promoted hair growth in preclinical tests, comparable to minoxidil 2%.
11 citations
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January 2017 in “Evidence-based Complementary and Alternative Medicine” This study investigated the effects of the herbal formulation DA-5512 on hair growth, finding that it significantly promotes dermal papilla cell proliferation and stimulates hair growth in mice while showing efficacy and safety in human trials compared to placebo and minoxidil (3%).
1 citations
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April 2025 in “JOJ Dermatology & Cosmetics” In this study, researchers evaluated the efficacy of a collagen booster used alongside CO2 fractional laser treatment for skin aging, finding that the combination treatment affected the vascularization and healing process of the skin on a healthy adult's forearm.
January 2026 in “Microsystems & Nanoengineering” This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.