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      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

    Research

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      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  147 upvotes 5 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community Minoxidil alternate approaches

      in Treatment  2 upvotes 5 months ago
      The conversation discusses hair loss treatments, including the use of 2.5mg Dutasteride, 1mg Finasteride, and Minoxidil 5%, with concerns about side effects like water retention and facial changes. The user is considering alternative Minoxidil applications, such as microneedling and sublingual Minoxidil, to minimize side effects.
      Compunded Oral Minoxidil, As Efficient As Tablet Variants?

      community Compunded Oral Minoxidil, As Efficient As Tablet Variants?

      in Minoxidil  146 upvotes 4 months ago
      The user discusses using compounded oral minoxidil due to the ineffectiveness and inconvenience of topical minoxidil for diffuse thinning. They question the efficacy of compounded minoxidil compared to original tablet forms and express concerns about the importance of excipients and binders.