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Glossary Polycaprolactone

biodegradable polyester used in medical applications

Polycaprolactone (PCL) is a biodegradable polyester with a low melting point, commonly used in medical applications such as sutures, drug delivery systems, and tissue engineering scaffolds. Its biocompatibility and slow degradation rate make it particularly useful for long-term implants and controlled release of medications.

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Research

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research Fabrication and Characterization of Electrospun Membranes Based on “Poly(ε-caprolactone)”, “Poly(3-hydroxybutyrate)” and Their Blend for Tunable Drug Delivery of Curcumin

29 citations , September 2020 in “Polymers”

This study found that electrospun poly(ε-caprolactone)/poly(3-hydroxybutyrate) blend fibers demonstrated nanometric dimensions and promising properties for drug delivery, with curcumin release linked to fiber morphology and processing parameters.

Cefazolin-Loaded Double-Shelled Hollow Mesoporous Silica Nanoparticles/Polycaprolactone Nanofiber Composites: A Delivery Vehicle for Regenerative Purposes

research Cefazolin-Loaded Double-Shelled Hollow Mesoporous Silica Nanoparticles/Polycaprolactone Nanofiber Composites: A Delivery Vehicle for Regenerative Purposes

6 citations , April 2022 in “Advanced Pharmaceutical Bulletin”

This study found that cefazolin-loaded silica nanoparticles embedded in polycaprolactone nanofibers successfully inhibited Staphylococcus aureus growth while maintaining stem cell viability, suggesting their potential use in wound healing.

In Vivo Hair Growth Promotion Effects of Cosmetic Preparations Containing Hinokitiol-Loaded Poly(ε-Caprolactone) Nanocapsules

research In vivohair growth promotion effects of cosmetic preparations containing hinokitiol-loaded poly(ε-caprolacton) nanocapsules

32 citations , January 2008 in “Journal of Microencapsulation”

In this study, nanocapsule-based preparations containing hinokitiol promoted hair growth in mice comparably to Minoxidil solution, as indicated by photographic and histological analysis.

research Electrospun Scaffold of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration

23 citations , November 2021 in “Journal of Bionic Engineering”

This study found that PCL-Col/ZnO fibrous scaffolds enhanced wound healing and exhibited antibacterial properties, making them promising for use as a wound dressing.

research Poly (ɛ‐caprolactone)–chitosan–poly (vinyl alcohol) nanofibrous scaffolds for skin excisional and burn wounds in a canine model

11 citations , January 2018 in “IET Nanobiotechnology”

In this study, poly (ɛ-caprolactone)–chitosan–poly (vinyl alcohol) nanofibrous scaffolds used on canine skin wound models were found to significantly accelerate healing rates of excision and burn wounds, without inducing immunogenic reactions.

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