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research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research Pneumatic Skin Flattening: A Novel Technology for Marked Pain Reduction in Hair Removal with High Energy Density Lasers and IPLs
Pneumatic Skin Flattening (PSF) significantly reduces pain during laser and IPL hair removal.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Consensus Report on the Use of PN-HPT (Polynucleotides Highly Purified Technology) in Aesthetic Medicine
Experts recommend using PN-HPT™ for skin rejuvenation in various body areas but have less agreement on initial facial treatment cycles.
research The CAP1/Prss8 Catalytic Triad Is Not Involved in PAR2 Activation and Protease Nexin-1 (PN-1) Inhibition
CAP1/Prss8 does not activate PAR2 or inhibit PN-1.
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community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community I am putting my hair loss treatment on hold until my mental health is better.
OP is pausing hair loss treatments to focus on mental health due to anxiety and side effects from RU58841. They plan to try topical finasteride and minoxidil after recovering from pneumonia.
community One year 2.5mg Minoxidil 1.25mg finasteride
A user shared progress pictures after one year of using 2.5mg Minoxidil and 1.25mg Finasteride for hair loss. The discussion includes suggestions for additional treatments like dermastamping, dutasteride, and increasing Minoxidil dosage, with mixed opinions on the effectiveness of current treatments.
community 2ish years of oral min, 1 year of fin. We're getting there lads
The conversation is about a user's progress with hair regrowth using oral minoxidil and finasteride over two years. The user experienced significant improvement without side effects, except for increased libido, and plans to continue treatment.
community Reverse Tressless...LOL O_O O_O
A person with a full head of hair chose to laser it off, sparking disbelief and discussions about hair loss treatments like Minoxidil and Finasteride. Many users questioned the decision, suggesting it might be a troll post or an extreme reaction to balding concerns.