research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
Search
forLearn
0 / 0 results — no results
Research
5 / 1000+ results research Pneumatic Skin Flattening: A Novel Technology for Marked Pain Reduction in Hair Removal with High Energy Density Lasers and IPLs
Pneumatic Skin Flattening (PSF) significantly reduces pain during laser and IPL hair removal.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Consensus Report on the Use of PN-HPT (Polynucleotides Highly Purified Technology) in Aesthetic Medicine
Experts recommend using PN-HPT™ for skin rejuvenation in various body areas but have less agreement on initial facial treatment cycles.
research The CAP1/Prss8 Catalytic Triad Is Not Involved in PAR2 Activation and Protease Nexin-1 (PN-1) Inhibition
CAP1/Prss8 does not activate PAR2 or inhibit PN-1.
Community Join
5 / 436 results
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community I am putting my hair loss treatment on hold until my mental health is better.
OP is pausing hair loss treatments to focus on mental health due to anxiety and side effects from RU58841. They plan to try topical finasteride and minoxidil after recovering from pneumonia.
community was thinking of buying this shampoo to replace my current one so i dont have to use min separately. opinions?
The conversation is about hair loss treatments, specifically discussing the effectiveness of shampoos with Minoxidil and DHT-blocking properties. Users suggest using Minoxidil, tretinoin, and microneedling for hair regrowth, while recommending ketoconazole shampoo for scalp health.
community A 2005 Hairloss Forum Describing How Close We Are To A Cure
Hair loss treatments like dutasteride, finasteride, minoxidil, and RU58841 are discussed, with mixed results and ongoing hope for better solutions. Users express skepticism about a cure, sharing experiences with various treatments and lifestyle changes.
community Bryan Johnson shares information on his hair loss stack
Bryan Johnson uses topical dutasteride, minoxidil, and microneedling for hair loss. Users discuss treatment effectiveness and side effects, debating topical versus oral dutasteride efficacy.