42 citations
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February 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that PNU 157706 is a highly potent inhibitor of human 5α-reductase enzymes, showing a stronger and longer-lasting antiprostatic effect in rats compared to finasteride.
39 citations
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January 2006 in “Journal of Cosmetic and Laser Therapy” This study found that pneumatic skin flattening (PSF) significantly reduces pain and post-treatment erythema during high-energy IPL and laser hair removal while enhancing treatment efficacy.
35 citations
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October 2004 in “Biology of Reproduction” This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.
14 citations
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August 2020 in “Journal of cosmetic dermatology” This consensus report provides detailed recommendations for using Polynucleotides Highly Purified Technology™ in aesthetic skin rejuvenation, highlighting its potential as a biostimulatory booster for face and body revitalization.
14 citations
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August 2014 in “The FASEB Journal” This study found that the catalytically inactive serine protease CAP1/Prss8 can still induce skin disorders in mice and is subject to inhibition by nexin-1, independent of its catalytic activity.
11 citations
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March 2018 in “Journal of cosmetic and laser therapy” In this study, pneumatic injections of non-cross-linked hyaluronic acid were associated with improvements in skin texture, pores, wrinkles, and transepidermal water loss in healthy female volunteers.
3 citations
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July 2021 in “Life science alliance” This study observed that disrupting the Pnkp gene in adult mice resulted in a premature aging-like phenotype, suggesting PNKP's vital role in maintaining normal growth and survival of certain progenitor cell populations.
1 citations
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July 1988 in “JAMA” This report describes a case of pneumonitis caused by metronidazole in a 42-year-old woman hospitalized with no known drug hypersensitivity.
August 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, combining Polynucleotides High Purification Technology with hyaluronic acid significantly reduced atrophic post-acne scar areas and improved Goodman-Baron scores in a majority of treated patients over six months, reaffirming the approach's beneficial effects in a real-world outpatient setting.
February 2026 in “The Journal of Sexual Medicine” In this case report, goserelin, a GnRH agonist, was effective in managing stuttering priapism and improving erectile function in a patient with sickle cell disease, suggesting potential for last-line treatment.
July 2024 in “International journal of agriculture and food sciences research.” This study found that a hair conditioner using peptides from Pneumatophorus japonicus heads improved damaged hair's structure, gloss, and smoothness more effectively than a commercial wheat protein conditioner by increasing amino acid content and interacting with hair keratin.
January 2024 in “Veterinary Science and Medicine Journal” In this case report, a 1.5-year-old Pomeranian named Beb with respiratory and skin issues was diagnosed with pneumonia and demodecosis; following a two-week treatment including antibiotics, ivermectin, and supportive care, Beb's symptoms resolved, and hair regrowth was observed.
June 2017 in “Advances in intelligent systems and computing” This study developed a prototype pneumatic dual-cell implanter that successfully stacked and implanted cells in tests, reducing hand burden for operators, which may improve alopecia treatments compared to traditional hair transplantation.
7 citations
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December 2021 in “European Respiratory Review” This review covers the current status of the interstitial pneumonia with autoimmune features (IPAF) category, pointing out the need for revision of its criteria to establish it as a standalone diagnostic term, but reports no new clinical findings.
2 citations
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January 2023 in “Respiratory Medicine Case Reports” This case report identified drug-induced lung disease caused by minoxidil in a patient initially misdiagnosed with hypersensitivity pneumonitis, stressing the need for accurate medication history.
1 citations
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January 2015 in “Journal of Arthritis” This case report describes an 18-year-old girl with systemic lupus erythematosus who developed lupus pneumonitis, initially misdiagnosed as tuberculosis, and responded dramatically to corticosteroid treatment.
1 citations
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September 2013 in “The Journal of Dermatology” An 8-year-old girl developed a rare skin condition in a linear pattern on one side of her body after a lung infection, which improved with treatment.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” This expert opinion article presents insights from dermatologists and aesthetic physicians on using polynucleotides (Rejuran®) for skin hydration, rejuvenation, structural support, barrier repair, and scar remodeling, noting their favorable safety profile but highlighting the need for more robust evidence and research.
June 2026 in “Journal of Cutaneous and Aesthetic Surgery” In this case report, necrotic ulceration caused by Klebsiella pneumoniae at a pubic hair donor site was observed in a 52-year-old man following hair transplantation, highlighting the need for metabolic screening and culture-guided management to prevent complications in such procedures.
October 2025 in “International journal of research and scientific innovation” This case report highlights the importance of considering lupus pneumonitis as a differential diagnosis for respiratory symptoms in systemic lupus erythematosus, especially in areas endemic to tuberculosis.
4 citations
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April 2007 in “Journal of Pediatric Gastroenterology and Nutrition” This case report describes a 16-year-old liver transplant patient with previous chicken pox infection experiencing disseminated varicella zoster virus infection with pneumonia, highlighting the importance of early acyclovir treatment in immunocompromised patients.
3 citations
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March 2022 in “Annals of Medicine” This study suggests that telogen effluvium is more closely related to the severity of COVID-19 and associated inflammation than to hormonal factors, with women showing a higher prevalence.
This case report highlights a unique instance where the use of naproxen was associated with concurrent eosinophilic pneumonitis and diffuse alveolar hemorrhage, conditions not previously linked to NSAIDs.
2 citations
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July 2022 in “Cureus” This case report describes a rare patient with Sjogren's syndrome who experienced recurrent pneumothorax, resolved through surgical intervention, highlighting pneumothorax as an unusual complication of the condition.
March 2025 in “Buletin Veteriner Udayana” In this case report, a 2.5-year-old cat with scabies and bacterial pneumonia showed significant improvement in symptoms and hair regrowth following a treatment regimen including ivermectin, amoxicillin with clavulanic acid, diphenhydramine, methylprednisolone, and supportive therapies over 100 days.
March 2023 in “Medical Bulletin of Haseki” This study found no statistically significant differences in extracellular water and cardiac measurements between COVID-19 patients in intensive care and those on the ward, though the NICaS device might aid fluid management.
October 2022 in “Clinical Cosmetic and Investigational Dermatology” This case report describes Rumpel-Leede phenomenon in a patient without underlying conditions, occurring after pneumatic compression for venous thromboembolism prophylaxis, with spontaneous resolution upon stopping compression.
December 2020 in “Dermatology archives” This review discusses the challenge of linking cutaneous manifestations directly to COVID-19 infection and highlights the inadequate characterization of these skin lesions, reporting no new clinical results.
24 citations
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December 1997 in “Mayo Clinic proceedings” This report describes a case where a woman developed bronchiolitis obliterans organizing pneumonia and lupus potentially induced by carbamazepine, a reaction not previously documented.
13 citations
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September 2023 in “Medical Gas Research” This review explores the molecular mechanisms and potential roles of nitric oxide in COVID-19 therapy, but provides no new clinical results.