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Did you mean Planar Cell Polarity?

GlossaryPlanar Cell Polarity

coordinated orientation of cells within tissue plane

Planar Cell Polarity (PCP) refers to the coordinated orientation of cells along a tissue plane, rather than just up and down. This is crucial for various biological processes, such as the uniform direction of hair growth on the skin or the proper alignment of cells in the inner ear for hearing.

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research Functional Redundancy of Frizzled 3 and Frizzled 6 in Planar Cell Polarity Control of Mouse Hair Follicles

24 citations, January 2018 in “Development”

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

research Co-Opting Developmental Signaling Pathways to Promote Wound Healing

1 citations, January 2018 in “Recent clinical techniques, results, and research in wounds”

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

research Planar Cell Polarity-Dependent and Independent Functions in the Emergence of Tissue-Scale Hair Follicle Patterns

33 citations, June 2017 in “Developmental Biology”

Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.

research Celsr1 And Celsr2 Exhibit Distinct Adhesive Interactions And Contributions To Planar Cell Polarity

7 citations, January 2023 in “Frontiers in cell and developmental biology”

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

research Cell Polarization Defects in Early Heart Development

9 citations, July 2007 in “Circulation Research”

Defects in certain proteins cause major heart abnormalities during early development.

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