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research Temperature-dependent phase transition microemulsions for enhanced transdermal delivery of finasteride and silodosin

March 2025 in “Scientific Reports”

This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.

research Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition From Telogen to Anagen Phase

5 citations , March 2022 in “Frontiers in Cell and Developmental Biology”

This study found that exosomes derived from bovine colostrum promoted hair growth in mice by activating the Wnt/β-catenin pathway, with effects similar to minoxidil but without adverse effects.

Ginsenosides in Panax Ginseng Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation

research Ginsenosides in Panax ginseng Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation

January 2024 in “Biological & pharmaceutical bulletin”

In this study, Panax ginseng extract and its ginsenosides were found to stimulate the proliferation of hair-related cells and promote the transition from the telogen to the anagen phase, enhancing hair-shaft growth by suppressing BMP4 expression in human dermal papilla cells.

research Kartogenin regulates hair growth and hair cycling transition

2 citations , January 2022 in “International Journal of Medical Sciences”

In this study, kartogenin promoted hair growth by enhancing cell proliferation and migration in vitro and extended hair length in mice, suggesting its potential as a treatment for hair loss.

research An estrogen receptor pathwayregulates thetelogen-anagen hair follicle transition andinfluences epidermal cell proliferation (epidermis/estrogen/keratinocyte/differentiation/mesenchymal

January 1996

This study found that estradiol affects hair growth in mice by regulating the transition of hair follicles from rest to growth phases via the estrogen receptor pathway in the dermal papilla.

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Community Join

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community 20 years old: 6 months of 1MG Fin + 1 month back on topical Min - Shed phase sucks.

in Progress Pictures 23 upvotes 1 month ago

A 20-year-old is experiencing hair thinning after 6 months on finasteride and 1 month on topical minoxidil, noting a difficult shedding phase. Others suggest patience and possibly considering dutasteride if needed, while emphasizing the importance of gradual transitions between treatments.

community Oral 1mg Fin/ 2.5mg Min (Before/After)

in Progress Pictures 127 upvotes 7 months ago

The conversation discusses hair loss treatments, specifically the transition from topical to oral minoxidil and finasteride, and the associated shedding phase. Users advise patience and consistency, noting that shedding is common and improvement may take several months.

community Aminexil, Nanoxidil, Stemoxydine and Kopexil. Anyone use them?

1 upvotes 9 years ago

Aminexil, nanoxidil, stemoxydine, and kopexil are discussed as alternatives to minoxidil for hair growth, with concerns about dependence. Minoxidil is noted for its effectiveness in transitioning hair growth phases, but dependence is mainly linked to androgenic alopecia.

community My 1.5-year journey: Transitioning from Finasteride/Topical to Dutasteride + Oral Minoxidil (5mg)

171 upvotes 2 months ago

The user transitioned from finasteride and topical minoxidil to dutasteride and oral minoxidil, increasing the oral minoxidil dose to 5mg, which led to shedding but also new hair growth. They found oral treatments more effective and convenient, despite initial shedding, and are seeking advice on long-term results and experiences with similar transitions.

community Transition from Baby Hair to Normal Hair?

in Finasteride/Dutasteride 33 upvotes 2 years ago

The conversation discusses the slow transition from baby hair to normal hair while using finasteride and transitioning to dutasteride, with progress except for the crown area. It's mentioned that hair thickening can take years, with each growth cycle potentially making the hair thicker, and this process can span over 6 months or more.

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Learn

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learn HMI-115

Who can benefit the most from HMI-115: men, women, or people in transition? There is no published trial showing that any one group benefits most from HMI-115: the only released human efficacy data is a company press release on a 16-person Phase 1b, and it reported hair-count results for the 12 men only.

learn Stemoxydine

How does stemoxydine help stimulate new hair growth on the scalp? Stemoxydine stimulates new hair growth by promoting hair follicles to transition from the resting phase to the active growth phase.

learn Adenosine

nucleoside used for hair regrowth stimulant properties

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Bimatoprost

a synthetic prostamide used to treat eyelashes also shows promise for stimulating hair growth on scalp

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Finasteride

Finasteride Results Timeline: How Long It Takes to Work, Shedding Phases, and Expected Outcomes Trial data and community reports both put the first visible changes on finasteride at roughly 3 to 6 months, with the clearest results between 6 and 12 months; an early shedding phase is common and usually temporary. The benefit lasts only while the drug is taken, and it is prescription-only.

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