20 citations
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August 2020 in “Scientific Reports” In this study, low-dose BPA was associated with induced prostatic hyperplasia in rats, potentially mediated by COX-2 and L-PGDS through pathways involving cell proliferation and apoptosis.
18 citations
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June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” In this mouse study, hair growth defects associated with the Gk5 null allele were partially alleviated by simvastatin treatment, suggesting GK5 plays a key role in skin-specific cholesterol regulation.
35 citations
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January 2011 in “Journal of Biological Chemistry” This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.
This study found that UV radiation-induced fibroblast depletion in the skin is primarily due to a deregulated inflammatory response, with T cells aiding fibroblast survival under stress.
35 citations
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May 2015 in “Thrombosis Research” This review synthesizes knowledge on Prostaglandin E2's role in platelet biology and suggests that targeting PGE2 pathways could lead to personalized antiplatelet therapy without affecting hemostasis, but it presents no new results.