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research Effects of Silicone Oil Viscosity on the Physical Structure and Damage Mechanisms of Hair during Permanent Wave Treatment

February 2026 in “Journal of the Korean Society of Cosmetology”

This study found that the viscosity of silicone oil in hair treatments significantly affects wave curling performance and hair damage, with untreated and chemically treated hair showing different optimal viscosities.

research Structural change of keratin protein in human hair by permanent waving treatment

70 citations , June 1998 in “Polymer”

This study found that permanent waving treatment partially disrupts the α-helical structure in human hair microfibrils, primarily during the initial reduction phase, rather than just affecting disulphide bonds.

research Treatment of permanent chemotherapy-induced alopecia with low dose oral minoxidil

36 citations , May 2015 in “Australasian Journal of Dermatology”

This case report described cosmetically significant hair regrowth in a 39-year-old woman with permanent chemotherapy-induced alopecia after continuous oral minoxidil use.

research Intermolecular disulfide cross-linked structural change induced by permanent wave treatment of human hair with thioglycolic acid.

1 citations , January 2013 in “PubMed”

In this study, treating hair with thioglycolic acid was found to alter disulfide bond patterns in keratin-associated proteins, shifting them from an ellipsoidal to a near-spherical shape.

research A Study on Hair Damage Following the Change of Treating Treatment Procedure when Iron Permanent is Treated

January 2012 in “Jounal of The Korean Society of cosmetology”

Applying conditioner mid-treatment reduces hair damage during perms.

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Learn

6 / 801 results

learn Platelet-Rich Plasma

Are Platelet results permanent, or does hair loss return once treatment stops? Hair loss typically returns after stopping PRP treatment, as effects are not permanent.

learn Hair Transplant

What is the best treatment for hair loss, specifically regarding hair transplants? Providers say there is no single best treatment: the choice depends on the person, with minoxidil and finasteride the common medicines and FUE a common surgical option. Only a minority of the clinics surveyed call a transplant permanent, and surgery does not stop hair loss in the hair around the grafts.
Is a hair transplant permanent? Transplanted hair is generally permanent but requires ongoing care to maintain results.
How long do hair transplants last? Hair transplants are typically permanent, but surrounding hair may thin over time.

learn Scalp Micropigmentation

How long does a scalp micropigmentation session take? Each scalp micropigmentation session typically takes 2 to 4 hours.

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

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Community Join

5 / 903 results

community Are permanent hair gains even possible?

in Chat 13 upvotes 1 year ago

Hair regrowth from treatments like minoxidil, RU58841, and finasteride is not permanent; stopping these treatments typically results in hair loss resuming. Beard hair can become permanent with minoxidil use, unlike scalp hair, which requires ongoing treatment to maintain gains.

community RU58841 Permanently Fixed Balding In Unexpected Way.

in Satire 123 upvotes 10 months ago

The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.

community Do hair follicles permanently die?

in Question 4 upvotes 7 years ago

Hair follicles can experience regrowth with treatments like finasteride, minoxidil, Nizoral, dermarolling, collagen, and biotin, but some may not fully recover. Expectations should be managed as full regrowth to teenage levels may not be possible.

community Korean treatment that literally made me confident to tie my hair up.

in Treatment 30 upvotes 4 months ago

A user shared their positive experience with MoriTint, a Korean scalp micro pigmentation technique that enhances the appearance of hair density without being permanent. They now offer this service in Los Angeles and emphasize its benefits for those with thinning hair, while clarifying it is not suitable for those with significant hair loss or baldness.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

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Clinics

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