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research Diurnal Preference Predicts Phase Differences in Expression of Human Peripheral Circadian Clock Genes

28 citations , June 2015 in “Journal of circadian rhythms”

This study found that extreme morning and evening chronotypes exhibited significant differences in the timing of circadian clock gene expression in hair follicle cells.

research Effects of bright light exposure during daytime on peripheral clock gene expression in humans

5 citations , December 2016 in “International journal of biometeorology”

In this study, bright light exposure during the daytime did not significantly affect clock gene expression in humans, although Rev-erb-ß expression appeared stronger under bright light compared to dim light.

research The Peripheral Clock Regulates Human Pigmentation

81 citations , October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that silencing clock genes BMAL1 or PER1 in human hair follicles increased melanin content and melanocyte activity, suggesting these genes influence pigmentation.

research Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle

30 citations , March 2015 in “PLoS ONE”

This study found that thyroxine modulates peripheral molecular clock gene expression in human hair follicles, which may have implications for treating clock-related diseases in patients with thyroid dysfunction.

research Peripheral Skin Temperature and Circadian Biological Clock in Shift Nurses after a Day off

49 citations , April 2016 in “International journal of molecular sciences”

This study found that shift nurses exhibited lower circadian variations compared to daytime nurses, indicating an adjustment of their biological clocks to continuous shift schedules.

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community What can be the real reason of Finasteride SE ?

18 upvotes 1 year ago

Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.

community Why do people here trust Kevin Mann?

36 upvotes 6 years ago

Concerns about finasteride's side effects on neurosteroids and brain health, with skepticism towards Kevin Mann's advice. Users discuss using finasteride, minoxidil, and RU58841 for hair loss, with mixed opinions on their safety and effectiveness.

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi