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Did you mean Perifollicular Inflammation?

GlossaryPerifollicular Inflammation

swelling and irritation around hair follicles

Perifollicular inflammation refers to the swelling and irritation that occurs around hair follicles. This condition can lead to hair loss and is often seen in various types of alopecia, such as alopecia areata. It involves immune cells attacking the hair follicles, which can disrupt normal hair growth and cause damage to the follicle structure.

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research Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study

126 citations, April 2006 in “International Journal of Dermatology”

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

research Keratosis Follicularis Spinulosa Decalvans in a Family

32 citations, February 2008 in “Journal of the American Academy of Dermatology”

KFSD is a genetic disorder causing hair loss and skin issues, with no effective treatment.

research Fibrosing Alopecia in a Pattern Distribution

1 citations, July 2018 in “Elsevier eBooks”

FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.

research Lymphocytic Mediated Alopecia: Histological Classification by Pattern Analysis

29 citations, March 2001 in “Clinics in Dermatology”

Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.

Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia

research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia

22 citations, June 2012 in “PLOS ONE”

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

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community Follow up appointment with Donovan.

in Finasteride/Dutasteride 17 upvotes 11 months ago

The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.

community I just want to say Ru58841 saved my life.

in Chat 28 upvotes 1 year ago

A user's experience with hair loss and scalp inflammation, which was alleviated by using RU58841 along with finasteride and dutasteride. A theory of inflammation possibly being a cause of hairloss is also discussed.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 2 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community A hill on which I will die: The DHT itch absolutely exists

in Research/Science 210 upvotes 5 months ago

The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

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