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community Hair Regrowth Following a Wnt- and Follistatin- Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial: Scientific, Peer-Reviewed Dermatology Article Indexed with MEDLINE/PubMed

4 upvotes 12 years ago

A treatment containing Wnt and Follistatin was found to be safe and effective for hair regrowth in a Phase 1 clinical trial. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.

community New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell

13 upvotes 11 years ago

A new treatment using dermal sheath cup cells may regrow hair and could require repeat treatments every 8 years. Users discuss ongoing trials and plan to use finasteride and minoxidil until the treatment is available.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

124 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Good News, PP405 is out on Shopee

270 upvotes 6 months ago

A product called "PP405 Hair Follicle Serum" is being sold on Shopee, claiming to cure baldness without clinical trials or FDA approval, but users are skeptical and refer to it as "snake oil." Some users discuss testing the product's contents, while others share their experiences with hair loss treatments like finasteride.

community Has Anyone used deoxyribose sugar (gel) and seen notable results?

4 upvotes 1 year ago

Deoxyribose sugar gel is discussed as a potential hair loss treatment, but it lacks human trials and credible evidence. Users express skepticism and humor about its effectiveness compared to established treatments like minoxidil and finasteride.

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Research

5 / 1000+ results

research Alopecia: A review of laser and light therapies

40 citations , February 2012 in “Dermatology Online Journal”

This review discusses cases and research on paradoxical hair growth after laser hair removal and explores laser and light therapies for treating alopecia, but reports no new results.

research Homoeopathy a System of Holistic Healing as an Alternative Treatment for PCOS – a Review

6 citations , December 2021 in “International Journal of High Dilution Research - ISSN 1982-6206”

This review covers clinical studies on using homoeopathy to treat PCOS and concludes that further rigorous research is necessary to substantiate its effectiveness.

research Mesotherapy for Hair Loss-is it Useful? Review of Literature

January 2018 in “Archives of dermatology and skin care”

This review discusses the lack of adequate clinical trials evaluating the efficacy and safety of mesotherapy for cosmetic hair loss and reports no new results.

research Real World Evidence in Alopecia Areata: Current Management, Emerging Therapies and Future Challenges – A Narrative Review

June 2026 in “Dove Medical Press (Taylor and Francis Group)”

This paper reviews existing and emerging therapies for alopecia areata, describing the impact of targeted treatments in this field, and introduces a global network of disease registers to study the long-term safety and effectiveness of these new options.

Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms: The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III

research Serenoa repens (saw palmetto) for Lower Urinary Tract Symptoms (LUTS): The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III

July 2021

This review concludes that the global literature supports the efficacy and safety of lipidosterolic extract of Serenoa repens in treating lower urinary tract symptoms, comparable to alpha-blockers and 5α-reductase inhibitors.

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Learn

9 / 9 results

learn Pyrilutamide

How long does it take to see visible results when using pyrilutamide topically? No published trial reports when pyrilutamide users first notice a change; its sponsor's studies measured results at 24 weeks, and all of those figures come from company announcements rather than peer-reviewed papers. Pyrilutamide is an unapproved experimental compound.
Can pyrilutamide be used by both men and women, or only in specific cases? Pyrilutamide (KX-826) is an investigational topical anti-androgen that has been trialled in both men and women, but it is not approved for hair loss anywhere; the company reports that its China Phase III trial in men met its primary endpoint, but the data come from sponsor announcements rather than peer-reviewed journals, and long-term safety is unknown.

learn Setipiprant

Is Setipiprant taken orally or applied topically, and what do studies show about its results? Every published human study of setipiprant used oral tablets; no peer-reviewed trial has tested a topical version. Results were inconsistent in seasonal allergic rhinitis, and the one controlled hair-loss trial (DuBois 2021, 169 men, 24 weeks) found no significant regrowth. It is an experimental, unapproved compound.

learn HMI-115

Is HMI-115 considered a safe option, or does it have strong side effects? HMI-115 is an experimental injected antibody, not a hormone blocker: the one published trial (in endometriosis) reported an acceptable 12-week tolerability profile with no treatment-related serious adverse events, and no peer-reviewed safety data exists for its use in hair loss.

learn Bimatoprost

Can a lash-growth serum like bimatoprost actually work for your scalp? Bimatoprost (Latisse) is approved for eyelashes, not the scalp; two Allergan phase 2 trials in men with androgenetic alopecia posted results to ClinicalTrials.gov but were never published in a peer-reviewed journal, so scalp use remains off-label and experimental.

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

learn sh-Polypeptide-7

learn Thymosin Beta 4

learn Beta Polypeptide

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