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GlossaryParathyroid Hormone-related Protein

regulates calcium levels and influences bone development

Parathyroid Hormone-related Protein (PTHrP) is a protein that plays a crucial role in regulating calcium levels in the body, similar to parathyroid hormone (PTH). It is involved in various physiological processes, including the development of bones and the regulation of cellular growth and differentiation. PTHrP is also significant in certain medical conditions, such as hypercalcemia of malignancy, where it can be produced in excess by some types of cancer cells.

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research A Topical Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor Antagonist Stimulates Hair Growth in Mice

26 citations, December 2006 in “Endocrinology”

A cream with a specific hormone blocker increases hair growth in mice.

research Clinical Uses for Calciotropic Hormones 1,25-Dihydroxyvitamin D3 and Parathyroid Hormone-Related Peptide in Dermatology: A New Perspective

23 citations, April 1996 in “PubMed”

Vitamin D3 and parathyroid hormone-related peptide may have important uses in skin treatments.

research Parathyroid Hormone-Related Peptide and the Hair Cycle: Is It the Agonists or the Antagonists That Cause Hair Growth?

9 citations, July 2014 in “Experimental Dermatology”

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

research The Parathyroid Hormone Second Receptor PTH2R and Its Ligand Tuberoinfundibular Peptide of 39 Residues TIP39 Regulate Intracellular Calcium and Influence Keratinocyte Differentiation

24 citations, March 2016 in “Journal of Investigative Dermatology”

TIP39 and PTH2R help control calcium levels and skin cell development.

research Hair Biology

33 citations, August 2018 in “Facial Plastic Surgery Clinics of North America”

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

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in Finasteride/Dutasteride 26 upvotes 3 months ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

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in Finasteride/Dutasteride 7 upvotes 3 years ago

A 39 year old female who has been taking finasteride for 1.5 months and is experiencing side effects such as muscle and butt shrinkage, and weight loss despite still having tight clothing. The user is seeking advice from those with knowledge of bodybuilding and hormones to help figure out the issue.