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    GlossaryParacrine Signaling (paracrine interaction)

    cells communicate by releasing molecules to nearby cells

    Paracrine signaling is a form of cell-to-cell communication where a cell produces signaling molecules, such as growth factors or cytokines, that affect nearby target cells within the same tissue. Unlike endocrine signaling, which involves hormones traveling through the bloodstream to distant targets, paracrine signals act locally, ensuring a rapid and specific response in the immediate cellular environment. This type of signaling is crucial in processes like wound healing, immune responses, and hair follicle regulation.

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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  732 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Just had this wild thought come into my head.

      in Satire  403 upvotes 8 months ago
      The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.

      community Why nobody uses 0.25% (2.5mg/ml)?

      in Treatment  65 upvotes 10 months ago
      The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

      community My hairloss stack, progress pics soon maybe for 1 year RU

      in Technology  49 upvotes 1 year ago
      The conversation is about a user's hair loss treatment routine, which includes RU58841 for 9 months and Dutasteride for 6 months, with other unspecified treatments considered extra. One user inquired about the source of RU58841.