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GlossaryPalmoplantar Keratoderma

thickening of skin on palms and soles

Palmoplantar Keratoderma (PPK) is a group of skin conditions characterized by the thickening of the skin on the palms of the hands and the soles of the feet. This thickening, known as hyperkeratosis, can be either inherited or acquired and may cause discomfort, pain, or difficulty in movement.

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research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency

24 citations, July 2014 in “Journal of Investigative Dermatology”

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

research Case Report of Schöpf–Schulz–Passarge Syndrome Resulting from a Missense Mutation, p.Arg104Cys, in WNT10A

5 citations, December 2017 in “The Journal of Dermatology”

A new gene mutation caused a man's rare skin condition, Schöpf-Schulz-Passarge syndrome.

research Hair Disorders

November 2019 in “Harper's Textbook of Pediatric Dermatology”

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

research Common Topical Medications

October 2018 in “Springer eBooks”

The document concludes that various topical medications are effective for skin conditions but often cause skin irritation as a side effect.

research Papillon-Lefèvre Syndrome: A Rare Case Report of Two Brothers and Review of the Literature

11 citations, January 2018 in “Jaypee's international journal of clinical pediatric dentistry”

Papillon-Lefèvre Syndrome causes early tooth loss and skin issues, needing early dental diagnosis.

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