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Did you mean Palmoplantar Keratoderma?

Glossary Palmoplantar Keratoderma

thickening of skin on palms and soles

Palmoplantar Keratoderma (PPK) is a group of skin conditions characterized by the thickening of the skin on the palms of the hands and the soles of the feet. This thickening, known as hyperkeratosis, can be either inherited or acquired and may cause discomfort, pain, or difficulty in movement.

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research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency

24 citations , July 2014 in “Journal of Investigative Dermatology”

This study reports that a widespread founder SERPINB7 mutation underlies Nagashima-type palmoplantar keratosis, which is a common form of palmoplantar keratosis in Asian populations.

research Keratosis Follicularis Spinulosa Decalvans Associated with Acne Keloidalis Nuchae and Tufted Hair Folliculitis

35 citations , January 2008 in “American Journal of Clinical Dermatology”

This case report further supports the association of keratosis follicularis spinulosa decalvans with acne keloidalis nuchae and tufted hair folliculitis.

research A novel mutation in the connexin 26 gene (GJB2) in a child with clinical and histological features of keratitis–ichthyosis–deafness (KID) syndrome

34 citations , September 2010 in “Clinical and Experimental Dermatology”

This study identified a new heterozygous mutation in the connexin 26 gene (c.263C>T; p.Ala88Val) in a premature neonate with KID syndrome, who later died from complications.

research Case report of Schöpf–Schulz–Passarge syndrome resulting from a missense mutation, p.Arg104Cys, in WNT10A

5 citations , December 2017 in “The Journal of Dermatology”

This report describes a unique case of Schöpf–Schulz–Passarge syndrome in a Taiwanese man linked to a previously unreported homozygous WNT 10A mutation, underscoring its role in ectodermal dysplasia.

research Oral Treatment of Keratinizing Disorders of Skin and Mucous Membranes With Etretinate

31 citations , February 1982 in “Archives of dermatology”

This study found that oral etretinate improved skin conditions like erythrodermic and pustular psoriasis, although less so for psoriasis vulgaris and lichen planus, with notable side effects including cheilitis and mucous membrane dryness.

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