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Research

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research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors

16 citations , November 2018 in “The journal of pain/Journal of pain”

This study found that in a rat model, 14,15-EET may alleviate central poststroke pain by enhancing thalamic inhibition through neurosteroid signaling, potentially outperforming gabapentin in early-stage treatment.

research The Effect of Local Skin Precooling on Alleviating Injection Site Pain in Patients With Androgenetic Alopecia Receiving a Scalp Nerve Block

March 2025 in “Pain Physician”

This retrospective study found that applying local skin precooling before scalp nerve block significantly reduced injection site pain during PRP mesotherapy for patients with androgenetic alopecia, compared to those who did not receive precooling, thus improving patient comfort and compliance.

research Low-Level Light/Laser Therapy Versus Photobiomodulation Therapy

433 citations , April 2015 in “Photomedicine and laser surgery”

This editorial discusses the terminology and distinctions between Low-Level Light/Laser Therapy and Photobiomodulation Therapy but reports no new clinical findings.

research Skin Hyperpigmentation in Complex Regional Pain Syndrome (CRPS) (P3.315)

1 citations , April 2015 in “Neurology”

This study found that hyperpigmented skin changes resembling Schamberg’s purpura occur in areas affected by CRPS and can also appear on mirror-image locations of unaffected limbs, potentially improving with the condition's treatment.

research Prospective, randomized, double-blind, controlled trial of laser laparoscopy in the treatment of pelvic pain associated with minimal, mild, and moderate endometriosis

3 citations , June 1995 in “International Journal of Gynecology & Obstetrics”

This paper cites a prospective, randomized, double-blind, controlled trial investigating laser laparoscopy for pelvic pain associated with minimal to moderate endometriosis but reports no new results.

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Community Join

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community Solution for male pattern baldness

245 upvotes 9 months ago

A new hair loss treatment claims a 539% improvement over placebo, but skepticism remains due to lack of substantial evidence and reliance on percentage figures. Users discuss the effectiveness of existing treatments like Minoxidil and Finasteride, expressing doubt about the new solution's impact.

community Anyone notice pain in scalp alongside hairloss?

10 upvotes 1 month ago

Scalp pain alongside hair loss may indicate inflammation rather than just male pattern baldness. Treatments mentioned include triamcinolone acetonide, fluocinonide, Head & Shoulders shampoo, aloe vera gel, finasteride, and 2% Nizoral.

community Chest pain on Oral minoxidil (18M)

in Minoxidil 38 upvotes 7 months ago

An 18-year-old experienced chest pain, headaches, and vomiting after taking oral minoxidil for hair loss. They reduced the dosage, felt better, but experienced sharp chest pain again after increasing it, and are advised to stop the medication and see a doctor.

community Testicular pain/discomfort....how long will this last? (29/m)

5 upvotes 9 years ago

A user experienced testicular pain after taking finasteride for hair loss and considered lowering the dose to 0.25mg to manage side effects. They also considered adding minoxidil to their routine while seeking advice on whether to continue or stop finasteride.

community Severe Testicular Pain After 2 Weeks on Oral Finasteride – Is This Normal?

in General 30 upvotes 6 months ago

A user experienced severe testicular pain after two weeks on oral finasteride. Another user suggested that while rare, this side effect can occur and recommended considering topical finasteride if the pain persists.

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Learn

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learn Scalp Micropigmentation

Will I experience pain after the scalp micropigmentation treatment? You may feel discomfort during the procedure and soreness afterward.

learn Hair Transplant

Will I feel pain during a hair transplant? Clinics say local anesthetic keeps the procedure mostly comfortable; the injections sting, and soreness afterwards is common.
How long does pain last after a hair transplant? Mild discomfort after a hair transplant typically lasts a few days to a week.
How can I manage pain after a hair transplant? Clinics advise taking the pain relief your surgeon prescribes or approves. Ask before using anti-inflammatories such as ibuprofen, which some surgeons avoid around surgery.
All 4 questions on Hair Transplant →

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Clinics

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All 27 clinic results →

Experts

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Hair System Specialist
Suparno Paine
Kolkata, West Bengal, India

Suparno Paine