research LPA-producing enzyme PA-PLA1α regulates hair follicle development by modulating EGFR signalling
The enzyme PA-PLA1α is important for proper hair follicle development.
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5 / 1000+ resultsresearch Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6
This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.
research LPA3, a unique G protein-coupled receptor for lysophosphatidic acid
This review discusses the role of LPA(3) in embryo implantation and its genetic connection with prostaglandin signaling, but reports no new clinical results.
research Lysophospholipid Mediators in Health and Disease
This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.
research Past and Future Strategies for GPCR Deorphanization
This chapter reviews current and future strategies for identifying ligands and functions of orphan G protein-coupled receptors, but it reports no new experimental results.
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