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GlossaryVaniqa (eflornithine)

topical cream that slows facial hair growth in women

Vaniqa is a topical cream containing eflornithine hydrochloride, used to reduce unwanted facial hair in women. It works by inhibiting an enzyme involved in hair growth, thereby slowing down the rate of hair production.

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research The Retarded Hair Growth Mutation in Mice Is an Allele of Ornithine Aminotransferase

9 citations, January 2014 in “Molecular Genetics and Metabolism Reports”

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

research Metabolomic Biomarkers in Women with Polycystic Ovary Syndrome: A Pilot Study

43 citations, July 2012 in “Molecular human reproduction”

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

research Hair Loss in Older Women: Supplement to Increase Scalp Hair Thickness and Reduce Hair Loss

January 2017 in “Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods”

The supplement reduces hair loss and increases hair thickness in older women.

research Regulation Mechanisms of Hair Growth

25 citations, April 2015 in “Current problems in dermatology”

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

research Elevated Ornithine Decarboxylase Activity Promotes Skin Tumorigenesis by Stimulating the Recruitment of Bulge Stem Cells but Not via Toxic Polyamine Catabolic Metabolites

17 citations, July 2013 in “Amino Acids”

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

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community I am having Success with RU58841 and 1mm Derma Roller

in Microneedling 19 upvotes 3 years ago

A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.