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Research

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research Leuprolide and estrogen versus oral contraceptive pills for the treatment of hirsutism: a prospective randomized study.

74 citations , December 1995 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that treatment with leuprolide plus cyclic estrogen/progestin may lead to a faster and greater improvement in hirsutism compared to a standard oral contraceptive regimen.

research YouTube and the implementation and discontinuation of the oral contraceptive pill: A mixed-method content analysis

6 citations , May 2024 in “PLoS ONE”

In this study, content analysis of German YouTube videos revealed that women frequently experience both positive and negative symptoms related to oral contraceptive use and discontinuation, with bodily sensations often influencing their decisions to start or stop the pill.

research Knowledge and beliefs about the use/abuse of oral contraceptive pills among males: A mixed-method explanatory sequential study in community pharmacy settings

3 citations , May 2021 in “PloS one”

This study found that Jordanian males use oral contraceptive pills, particularly for bodybuilding, based on recommendations from gym coaches, highlighting unexpected uses of these medications.

Oral Contraceptive Pill Treatment Alters Gene Expression of Inflammatory Markers in Polycystic Ovary Syndrome Women

research Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women

2 citations , February 2023 in “BMC women's health”

In this study, oral contraceptive use in women with PCOS increased the expression of certain inflammatory gene markers, which were positively associated with metabolic abnormalities.

research The Use/Abuse of Oral Contraceptive Pills Among Males: A Mixed-Method Explanatory Sequential Study Over Jordanian Community Pharmacists

1 citations , March 2021 in “medRxiv (Cold Spring Harbor Laboratory)”

This study provided insight into unexpected uses and abuse of oral contraceptive pills by Jordanian males, primarily for bodybuilding, as reported by community pharmacists.

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Community Join

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community Questions about oral Minoxidil (pill and sublingually)

5 upvotes 4 years ago

Oral minoxidil is considered more convenient and effective than topical or sublingual forms, with users reporting positive results and minimal side effects. Some users experience side effects with oral minoxidil and opt for sublingual or topical methods instead.

community Switched to oral combo pill (1.2 mg fin, 3 mg min, vitamins) from topical and wanted to share my thoughts.

in Treatment 3 upvotes 7 months ago

Switching from topical to an oral combo pill (1.2 mg finasteride, 3 mg minoxidil, vitamins) improved hair thickness without noticeable side effects. The user appreciates the convenience of a single daily pill over twice-daily topical applications.

community Thoughts about ORAL ketoconazole? (pills)

8 months ago

Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

community Pills for life Dutasteride 2.5mg+5mg oral Minoxidil 🤑

in Satire 37 upvotes 1 year ago

The conversation discusses using Dutasteride, oral Minoxidil, and other medications for hair loss, with the user expressing satisfaction despite potential side effects. The user prefers these treatments to maintain a youthful hairline, despite others suggesting alternative methods.

community Progress since July 2025. Oral min 5mg, fin 1.1mg, biotin 1mg combo pill.

in Progress Pictures 54 upvotes 9 months ago

The user shared progress pictures showing hair improvement since July 2025 using a combo pill containing oral minoxidil 5mg, finasteride 1.1mg, and biotin 1mg, with no noticeable side effects. The user feels more confident and has not experienced any shedding.

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Learn

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Spironolactone

Is spironolactone better for hair regrowth as a pill or as a scalp solution? Oral spironolactone has the stronger published evidence for hair regrowth; topical versions cause fewer systemic side effects but have been studied far less, and no trial has compared the two head to head.

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

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Clinics

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