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      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

    Research

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      community Haircafe on why microneedling is bad for hair growth

      in Microneedling  157 upvotes 8 months ago
      Microneedling combined with minoxidil and finasteride shows significant hair regrowth, though opinions on its effectiveness vary. Some users report substantial benefits, while others highlight the need for more research and consistency in application.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  402 upvotes 6 days ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community What else is good. Besides the big 3.

      in Chat  34 upvotes 6 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2449 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Dut/Minox/Needling to Dut/Oral Minox/Tretinoin/Needling

      in Minoxidil  3 upvotes 11 months ago
      The user had been using Minoxidil and Dutasteride with micro-needling but experienced hair loss after switching Minoxidil brands. Their doctor prescribed oral Minoxidil and Tretinoin, but the pharmacist suggested isotretinoin might be a more cost-effective alternative.