learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
research A New Path in Defining Light Parameters for Hair Growth: Discovery and Modulation of Photoreceptors in Human Hair Follicle 70 citations, April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
research Osteopontin Gene Is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner 17 citations, December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
research Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation 12 citations, January 2022 in “Cells” Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.
research Osteopontin: A New Facilitating Factor in Alopecia Areata Pathogenesis? 7 citations, January 2015 in “PubMed” Osteopontin may play a role in alopecia areata, but its levels don't predict treatment success.
research Serum Level of Osteopontin in Patients with Alopecia Areata and Its Correlation with Ocular Changes 2 citations, January 2021 in “The Scientific Journal of Al-Azhar Medical Faculty Girls” Alopecia areata patients have higher osteopontin levels and more eye changes, but their vision remains unaffected.
community My Theory Regarding a Cause and Cure for Androgenetic Alopecia in Treatment 97 upvotes 5 years ago Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.