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GlossaryEstrogen

group of hormones regulating female reproductive system and traits

Estrogen, also spelled oestrogen, is a group of hormones primarily responsible for the development and regulation of the female reproductive system and secondary sexual characteristics. It plays a crucial role in the menstrual cycle, pregnancy, and bone health, and is also present in smaller amounts in males, where it helps regulate certain functions of the reproductive system and maintain bone density.

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Cross-Sex Hormone Therapy in Trans Persons Is Safe and Effective at Short-Term Follow-Up: Results from the European Network for the Investigation of Gender Incongruence

research Cross-Sex Hormone Therapy in Trans Persons Is Safe and Effective at Short-Term Follow-Up: Results from the European Network for the Investigation of Gender Incongruence

204 citations, May 2014 in “The Journal of Sexual Medicine”

Hormone therapy for trans individuals is effective and generally safe in the short term.

research Hormone Replacement Therapy and the Skin

138 citations, May 2000 in “Maturitas”

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

research The Effects of Estrogens on Linear Bone Growth

173 citations, May 2001 in “Human reproduction update”

Oestrogens are key for bone growth during puberty in both boys and girls.

research Estrogen Functions in Skin and Skin Appendages

68 citations, June 2005 in “Expert Opinion on Therapeutic Targets”

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Thyrotropin-Releasing Hormone and Estrogen Differentially Regulate Prolactin and Prolactin Receptor Expression in Female Human Skin and Hair Follicles In Vitro

research Thyrotropin-Releasing Hormone and Estrogen Differentially Regulate Prolactin and Prolactin Receptor Expression in Female Human Skin and Hair Follicles In Vitro

37 citations, March 2010 in “British Journal of Dermatology”

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

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community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 124 upvotes 10 months ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

in Insane 35 upvotes 1 year ago

A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

community Should I start Fin with these blood tests?

in Finasteride/Dutasteride 16 upvotes 1 year ago

A 25-year-old male with normal hormone levels is considering starting finasteride and minoxidil for hair loss but is concerned about high estradiol levels and potential side effects. Responses vary, with some suggesting blood tests before starting treatment and others emphasizing individual tolerance and the importance of consulting a doctor.

community Quiting minoxidil fansteride and only Stemoxydine and monthly dermapen 1.5 MM

in Research/Science 2 upvotes 2 years ago

User quit minoxidil and finasteride, starting stemoxydine, dermastamp, and dermapen for hair loss. Seeks advice on alternatives, avoiding androgen disruptors and vasodilators/vasoconstrictors.

community Aromatase Upregulation along with DHT down regulation could possibly hold the cure

in Microneedling 7 upvotes 2 years ago

The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.

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