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    Glossary Notch signaling

    cell communication system regulating development and tissue maintenance

    Notch signaling is a fundamental communication system used by cells to control various developmental processes and maintain tissue homeostasis. It involves interactions between neighboring cells through the Notch receptor and its ligands, leading to changes in gene expression that influence cell fate decisions, such as differentiation, proliferation, and apoptosis. This pathway is crucial in many biological contexts, including the development of hair follicles and the regulation of stem cells.

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    1. Melanoblasts' Proper Location and Timed Differentiation Depend on Notch/RBP-J Signaling in Postnatal Hair Follicles 2008 · 70 citations
    2. The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development 2016 · 16 citations
    3. Hemidesmosomes and Notch signaling regulate epidermal differentiation via delamination Development · 2026
    4. RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome The American Journal of Human Genetics · 2012 · 112 citations
    5. Accelerated Endothelial to Mesenchymal Transition Increased Fibrosis via Deleting Notch Signaling in Wound Vasculature Journal of Investigative Dermatology · 2017 · 26 citations
    6. 15. Hair and Nails Medical & surgical dermatology · 2009
    7. Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis Genes & development · 2010 · 95 citations
    8. Hair Follicle Stem Cells Maintain the Differentiation Refractory Niche for Co-Occupant Melanocyte Stem Cells by Regulating Retinoid Metabolic Process Social Science Research Network · 2019
    9. Epidermal Notch signalling: differentiation, cancer and adhesion Current opinion in cell biology · 2008 · 253 citations
    10. Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for β-catenin and Notch signalling Developmental biology · 2008 · 84 citations
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