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research Can we halt male androgenetic alopecia progression without antiandrogenic drugs?

1 citations , December 2019 in “Dermatologic Therapy”

This article explores whether it's possible to stop the progression of male androgenetic alopecia without using antiandrogenic drugs and reports no new clinical findings.

research Diagnostic challenges in determining alopecia areata

1 citations , October 2013 in “Expert Review of Dermatology”

This paper reviews the differential diagnoses and diagnostic tests to distinguish alopecia areata from other types of hair loss, without providing new clinical findings.

research Development and Evaluation of a Niosome-Integrated Microneedle System for Targeted Follicular Delivery of Ketoconazole in Alopecia Therapy

February 2026

This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.

research Dermatologic Manifestations of Polycystic Ovary Syndrome

76 citations , January 2007 in “American Journal of Clinical Dermatology”

This review discusses the dermatologic features of PCOS as potential early indicators of the syndrome and notes that treatment of these conditions may enhance quality of life and psychological well-being, but it reports no new clinical results.

research Red ginseng (Panax ginseng Meyer) oil: A comprehensive review of extraction technologies, chemical composition, health benefits, molecular mechanisms, and safety

11 citations , December 2021 in “Journal of Ginseng Research/Journal of ginseng research”

This review discusses the chemical composition, potential health benefits, and extraction methods of red ginseng oil, and reports no new clinical results but emphasizes safety and proposed molecular mechanisms.

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Community Join

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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Learn

7 / 800 results

learn GT20029

Experimental topical drug designed to break down androgen receptors

Is GT20029 safe and effective for both men and women with androgenic alopecia? Not known yet. GT20029 is an experimental drug tested only in men: in one 12-week trial two of four regimens beat placebo with similar side-effect rates, and long-term safety and effects in women or pregnancy are unstudied.

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss, although its US label says it should not be used in women. The one randomised trial (74 women, 2025) found it added no benefit to oral minoxidil, and the drug needs liver monitoring because its label warns of severe and fatal liver injury; it is contraindicated in pregnancy.

learn TDM-105795

How does TDM-105795 differ from more established hair loss ingredients when included in experimental or emerging treatments? TDM-105795 is an experimental topical drug described as a thyroid-receptor agonist, unlike minoxidil or finasteride. It has one 16-week Phase 2 trial in 71 men, with no statistical test or peer-reviewed results published and no head-to-head comparison.

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Nanoxidil

learn Follistatin

How does follistatin compare to finasteride or dutasteride for treating androgenic alopecia? Finasteride and dutasteride are prescription drugs with large controlled trials showing they lower DHT and slow androgenic hair loss, at the cost of documented hormonal side effects; follistatin targets a different, regenerative pathway but has only one small phase 1 human trial behind it, so it is experimental with unknown safety rather than a comparable alternative.

learn RU58841

Experimental topical anti-androgen sold as a research chemical

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Clinics

1 / 5 results

Hair Loss Treatments
Dr Joydeep Roy's Skin Clinic, New S.S.Medicos, (near Cachar high school), Malugram/ Drugs Corner, itkhola near Cachar CollegeSilchar, Assam · IN

Experts

1 / 4 results

Dermatologist
Andi Iryanti, M. Biomed
Indonesia

Andi Iryanti, M. Biomed