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GlossaryNFATc1

protein regulating gene expression in immune and hair follicle cells

NFATc1, or Nuclear Factor of Activated T-Cells, cytoplasmic 1, is a protein that plays a crucial role in the regulation of gene expression in immune cells, particularly T-cells. It is involved in the activation of immune responses and has also been implicated in various biological processes, including the development and function of hair follicles.

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research Calcineurin/NFATc1 Signaling Links Skin Stem Cell Quiescence to Hormonal Signaling During Pregnancy and Lactation

40 citations, April 2014 in “Genes & Development”

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

research Investigation of the Role of SIRT3, SIRT7, NFATC1, and PDL-1 Genes in Androgenetic Alopecia

July 2024 in “Research Square (Research Square)”

SIRT3 and SIRT7 decrease, while NFATC1 and PDL-1 increase in Androgenetic Alopecia.

MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata

research MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata

January 2023 in “Annals of dermatology/Annals of Dermatology”

A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.

research Epidermal Stem Cell Diversity and Quiescence

168 citations, August 2009 in “EMBO molecular medicine”

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

52 citations, February 2012 in “PloS one”

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

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community switched from topical to oral minoxidil (topical mixed with water) 3 months ago and aside from being much easier i’ve also had much more density overall. My results aren’t even finished yet!

in Progress Pictures 2 years ago

This user discussed using oral minoxidil as a hair loss treatment, and was cautioned against mixing topical minoxidil with water and drinking it due to potential side effects and risks. Other users shared their concerns about the dangers of self-prescribing medications without consulting a doctor.