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research Data from Tumor Necrosis Factor-Alpha and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

March 2023

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

research Data from Tumor Necrosis Factor-Alpha and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

March 2023

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

research IL-36γ Drives Skin Toxicity Induced by EGFR/MEK Inhibition and Commensal Cutibacterium Acnes

32 citations, December 2019 in “The Journal of clinical investigation/The journal of clinical investigation”

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

research Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers

3 citations, January 2011 in “Annals of Dermatology”

Blocking EGFR in skin cells doesn't majorly increase inflammation markers.

research Cyclophosphamide-Associated Acneiform Drug Eruption in a Patient with Multiple Myeloma

5 citations, September 2011 in “Journal of the American Academy of Dermatology”

A patient's skin eruption was caused by the cancer drug cyclophosphamide and improved after stopping the drug.

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community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 411 upvotes 4 months ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Hair is kinking rapidly following hair loss

in Update 1 upvotes 1 month ago

Hair loss has slowed, but uneven growth and kinking persist despite using keto/nizoral shampoo and clotrimazole. Stress and anxiety might be contributing factors.