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GlossaryNeuroendocrine Tumor

cancer arising from hormone-producing nerve cells

A Neuroendocrine Tumor (NET) is a type of cancer that arises from neuroendocrine cells, which are specialized cells that have traits of both nerve cells and hormone-producing cells. These tumors can occur in various parts of the body, including the gastrointestinal tract, pancreas, and lungs, and they can produce hormones that cause a range of symptoms depending on their location and the hormones they secrete.

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research Direct Cellular Reprogramming Enables Development of Viral T Antigen-Driven Merkel Cell Carcinoma in Mice

14 citations , February 2022 in “The Journal of clinical investigation/The journal of clinical investigation”

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

research First-In-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors

505 citations , October 2011 in “Journal of clinical oncology”

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Anti-Basal Cell Carcinoma Efficacy of a Topical Hedgehog Inhibitor Without Adverse Effects in Gorlin Syndrome Patients in a Phase 2 Randomized Controlled Trial

research Anti-Basal Cell Carcinoma Efficacy of a Topical Hedgehog Inhibitor Without Adverse Effects in Gorlin Syndrome Patients in a Phase 2 Randomized Controlled Trial

1 citations , April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

research LRIG1 as a Positive Prognostic Marker in Merkel Cell Carcinoma and Expression of Epithelial Stem Cell Markers

10 citations , July 2021 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin”

LRIG1 is linked to better survival in Merkel cell carcinoma.

research Disruption of Anthrax Toxin Receptor 1 in Pigs Leads to a Rare Disease Phenotype and Protection from Senecavirus A Infection

7 citations , March 2022 in “Scientific reports”

Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.

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community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 4 months ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 2 years ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

community After quitting min and fin I asked AI on how fix the mess I am in and it says:

in Technology 6 months ago

Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.

community how does my progress look 18M 3 months on fin 1mg daily

in Progress Pictures 277 upvotes 2 years ago

An 18-year-old male's successful hair regrowth after three months of using finasteride 1mg daily. He reported no side effects and other users expressed admiration and curiosity about his results.

community Fluridil vs Breezula?

in Treatment 14 upvotes 5 years ago

Comparing two upcoming topical hair loss treatments, Fluridil and Breezula, to determine which is most effective for treating hair loss, taking into consideration factors such as price, side effects, potential for hair growth, convenience of application, smell, greasiness, and styling after use.

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