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Neurosteroids

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research Studies on Neurosteroids XXIV: Determination of Neuroactive Androgens, Androsterone and 5α-Androstane-3α,17β-Diol, in Rat Brain and Serum Using Liquid Chromatography–Tandem Mass Spectrometry

13 citations , July 2008 in “Biomedical Chromatography”

The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.

research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System

1 citations , December 2021 in “Androgens”

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

research Cognitive Effects of Testosterone and Finasteride Administration in Older Hypogonadal Men

26 citations , August 2014 in “PubMed”

Testosterone improves mood and thinking skills; finasteride has no effect.

research Cognitive Effects of Testosterone and Finasteride Administration in Older Hypogonadal Men

August 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Testosterone and finasteride showed minor cognitive benefits in older men.

research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease

34 citations , December 2015 in “Neuroscience & Biobehavioral Reviews”

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

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community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

in Finasteride/Dutasteride 27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 3 months ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community Doctor says i shouldn't take fin because its "hormonal"

in Finasteride/Dutasteride 105 upvotes 1 year ago

A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 2 years ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

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