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GlossaryNeural Crest Stem Cells (NCSCs)

originate from the neural crest and can become various cell types

Neural Crest Stem Cells (NCSCs) are a type of multipotent stem cell that originate from the neural crest, a transient structure in vertebrate embryos. These cells have the remarkable ability to differentiate into a diverse range of cell types, including neurons, glial cells, melanocytes, and even some types of connective tissue. This versatility makes them crucial for the development of various tissues and organs, and they are a significant focus in regenerative medicine and developmental biology research.

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research Human Epidermal Neural Crest Stem Cells (hEPI-NCSC): Characterization and Directed Differentiation into Osteocytes and Melanocytes

91 citations, March 2011 in “Stem Cell Reviews and Reports”

Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.

research Hair Curvature: A Natural Dialectic and Review

28 citations, March 2014 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society”

The document concludes that hair curvature can be explained by the growth patterns caused by the shape and separation of cells in the hair follicle and is affected by specific molecular pathways.

research Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis

11 citations, February 2019 in “Stem cells international”

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

research Rapid Preparation of a Noncultured Skin Cell Suspension That Promotes Wound Healing

5 citations, March 2017 in “Cell and Tissue Banking”

Researchers developed a new method to quickly prepare skin cells that improve wound healing in rats.

research Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells

3 citations, August 2014 in “Cellular reprogramming”

Hair follicle stem cells need all reprogramming factors to become pluripotent.

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