16 citations,
May 2000 in “Endocrinology” A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
May 2005 in “Molecular Carcinogenesis” The study investigated the response of mitogen-regulated protein/proliferin (mrp/plf) gene family transcripts to tumor promoters in SENCAR mice. After applying tumor promoters like TPA and BPO to the skin, researchers observed significant increases in mRNAs for genes such as ornithine decarboxylase, junB, and egr1, particularly in response to TPA. Although mrp/plf-mRNA was not detected in Northern blot hybridizations, it was identified using RT-PCR in most TPA-treated and some BPO-treated animals. The predominant mRNA species were plf1 and mrp3. The study concluded that mrp/plf-mRNA was differentially expressed in response to tumor promoters and could serve as a biomarker for tumor-promoting effects in chemical carcinogenesis.
55 citations,
September 2017 in “Expert Opinion on Drug Discovery” Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.
The document is a guide for practitioners to successfully perform hair transplants using the FUE method.
A hair transplant using hair from the back of the head and pubic area was successful in creating a feminine hairline for a male-to-female transgender person.