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This study demonstrated that a c-Kit-CreER-driven mouse model confirms melanocyte stem cells as a genuine source of melanoma, paralleling human melanoma in heterogeneity and gene signatures.

In this study, researchers observed that dormant TRP-2+ melanoma cells in bone marrow can interact with CD8+ T cells in tumor-bearing ret transgenic mice, potentially influencing immune responses.

This study found that DHEA significantly inhibited growth and induced autophagy in a mouse melanoma cell line, but showed only muffled inhibition and induced apoptosis in a human melanoma cell line.

This study used atomic force microscopy to image surface structures of human epidermal melanocytes, hair follicle amelanotic melanocytes, and mouse melanoma cells, revealing differences in branch structure and granule distribution.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.