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      research Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors

      103 citations , October 2003 in “Birth Defects Research”
      This review discusses the multifactorial etiology of hypospadias, including genetic predispositions and possible environmental factors, and highlights the need for further studies on genetic and environmental contributions to its increasing prevalence, without presenting new findings.

      research Genetic factors in the etiology of intervertebral disc herniation and protrusion

      May 2024 in “International journal of medicine and psychology.”
      This study examines the significant role genetic factors play in the development of intervertebral disc herniation and protrusion and explores how advancements in molecular genetics and translational medicine might improve diagnosis, prevention, and treatment, ultimately aiming to enhance patient outcomes and quality of life.

      research Androgenetic alopecia: Update on etiology

      1 citations , March 2021 in “Dermatological reviews”
      This review discusses recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia in males, females, and children, but reports no new clinical results.

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      community Bruteforcing alopecia or the new advent of science progress

       22 upvotes 1 year ago
      Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

      community PP405 Phase 2a press release with early results

       700 upvotes 1 year ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 2 years ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Does dutasteride brand matters?

       4 upvotes 1 week ago
      Generic dutasteride should work as long as it contains the correct active ingredient, regardless of brand. In India, it's recommended to use trusted brands like Dr. Reddy's due to bioequivalence concerns.

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      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched