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research 344 Topical carbamide peroxide for treatment of mild to moderate acne vulgaris

April 2017 in “Journal of Investigative Dermatology”

This study found that 10% carbamide peroxide significantly reduced acne lesions compared to a vehicle solution, suggesting it as an effective and safe alternative to benzoyl peroxide for treating mild to moderate acne.

research Efficacy, safety and dose response of STS01, a topical controlled release nanoparticle formulation (dithranol/Prosilic), in adults with mild to moderate patchy alopecia areata: A randomised, double-blind, multicentre, phase 2 trial

April 2026 in “medRxiv”

In this phase 2 trial, STS01 1% significantly improved hair regrowth in patients with mild to moderate patchy alopecia areata compared to placebo, with a manageable skin irritation side effect profile.

research HAIR GROWTH ACTIVITY AND SAFETY TEST OF ETHOSOMAL GEL ETHYL ACETATE FRACTION OF NOTHOPANAX LEAVES (NOTHOPANAX SCUTELLARIUM MERR.)

1 citations , August 2017 in “Asian Journal of Pharmaceutical and Clinical Research”

The 1% ethyl acetate fraction ethosomal gel from Nothopanax scutellarium leaves promotes hair growth but can mildly irritate the skin.

research Derma rollers in therapy: the transition from cosmetics to transdermal drug delivery

19 citations , October 2020 in “Biomedical Microdevices”

This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.

research Highly efficient and compatible shampoo for use after hair transplant

4 citations , July 2015 in “Clinical, cosmetic and investigational dermatology”

In this study, a new hypertolerant shampoo significantly reduced scabbing and erythema after hair transplantation, demonstrating excellent skin compatibility and suitability for sensitive scalp care.

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Learn

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learn Tea tree

How does tea tree oil interact with the scalp environment in products designed for irritation, dandruff, or mild hair shedding? In one 4-week trial, a 5% tea tree oil shampoo reduced mild to moderate dandruff; anti-inflammatory effects have been seen only in lab studies. Tea tree oil itself can irritate the skin or cause allergy.

learn Capixyl

Capixyl: Does it have side effects? Or is it too good to be true? Capixyl may cause mild irritation or allergic reactions in some users.

learn Pyrilutamide

Are there any common side effects or scalp reactions to watch for when applying pyrilutamide? Company summaries describe mostly mild scalp irritation, but full adverse-event data have never been published and pyrilutamide is an unapproved investigational compound. Antiandrogens are not considered appropriate for anyone who is pregnant, may become pregnant or is breastfeeding.

learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Exosomes

Do exosomes work for people with mild hair loss or only in advanced cases? There is no approved exosome treatment for hair loss and no controlled trial in either mild or advanced cases; the argument that early thinning would respond better is based on follicle biology, not on results.

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Community Join

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community Liquid Minoxidil gave me seb derm on my eyebrows — will it mess up my scalp too if I use it on my temples?

in Minoxidil 71 upvotes 1 year ago

Liquid minoxidil caused mild seborrheic dermatitis on the user's eyebrows, likely due to propylene glycol. The user is considering switching to foam or oral minoxidil to avoid irritation on the scalp/temples.

community 14 months - 1mg fin & 5% topical minoxidil results

in Progress Pictures 452 upvotes 4 months ago

Significant hair regrowth was achieved using 1mg finasteride and 5% topical minoxidil over 14 months, with only initial shedding and mild scalp irritation as side effects. Consistency and early treatment are recommended for optimal results.

community 2 years of treatment with fin, dut and oral minoxidil

in Progress Pictures 6 upvotes 8 months ago

The user experienced chronic telogen effluvium and mild male pattern baldness, treated with finasteride, oral minoxidil, and later switched to dutasteride, which stopped excessive hair shedding. Other treatments like low-level laser therapy, hair loss shampoos (except ketoconazole), and supplements were ineffective.

community GHK-Cu is reducing my Seb Derm Flare

5 upvotes 2 months ago

GHK-Cu helped control Seborrheic Dermatitis and reduced scalp irritation, with no immediate change in hair fall or growth. Users reported reduced flakes and healthier skin using GHK-Cu topically.

community Effectiveness and Safety of Hair Growth Formulation Containing Tectona grandis L.f (Teak) Leaf Extract

in Chat 33 upvotes 1 year ago

Teak leaf extract shows potential as a mild hair growth promoter for androgenic alopecia, with similar positive trends to minoxidil but without significant side effects. It can be made at home using dried teak leaves and ethanol, though its effectiveness compared to other treatments like finasteride is debated.

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