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Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

July 2023

The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.

research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

August 2023 in “International Journal of Molecular Sciences”

The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.

Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1

research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1

1 citations, September 2012 in “Journal of Investigative Dermatology”

Aging reduces stem cell activation, leading to hair loss in mice lacking a specific enzyme.

research Dermal Fibroblasts Enhance Growth Factors Production by Androgens and Modulate Keratinocyte Proliferation and Differentiation

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Androgens increase growth factors in skin cells, which may lead to acne.

research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine

773 citations, August 2017 in “International Journal of Molecular Sciences”

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

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Community Join

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community Average r/tressless user preparing his scalp for minoxidil

in Microneedling 116 upvotes 1 year ago

Preparing the scalp for Minoxidil treatment by using a dermaroller to create microtears, as an alternative to traditional microneedling.

community Would taking Ketoconazole 2% shampoo before signs of male pattern baldness help delay hair loss?

in Research/Science 7 upvotes 1 year ago

The conversation is about a user considering the use of Ketoconazole 2% shampoo before showing signs of male pattern baldness (MPB) to potentially delay its onset, inspired by a YouTuber who uses the shampoo to reduce scalp DHT levels. The user's interest in this preventative measure stems from a family history of MPB.

community 3 Year Update (26m) (fin, min, micro needling, nizoral)

in Progress Pictures 155 upvotes 2 years ago

Hair loss treatment with finasteride, minoxidil, microneedling, and nizoral shows impressive results after 3 years. Dermatologist recommended starting with finasteride before adding other treatments.

community 9 months progress on fin and min

in Is this regrowth? 384 upvotes 4 months ago

User shared 9 months of progress using 1 mg finasteride and topical minoxidil, showing photos from different stages. Encouragement was given to continue the treatment.

community Let's be clear, does Finasteride stop MPB as long as it's taken?

in Finasteride/Dutasteride 170 upvotes 8 months ago

Finasteride is believed to slow down hair loss significantly, but may not completely stop it for everyone. Effectiveness and duration vary by individual, with some users experiencing positive results for over 10 years, while others see less benefit.

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