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This study reports that optimal follicular penetration in nanocarrier-assisted drug delivery for skin diseases occurs with carrier sizes between 300 and 650 nm, while certain traditional medicine practices have shown effectiveness in treating skin conditions.

This study confirmed that the novel solid lipid microparticle formulation of adapalene demonstrated follicular penetration potential and targeted particle erosion in sebum in in vitro tests.

In this study, lecithin-based microparticle formulations of minoxidil showed enhanced skin penetration and comparable hair growth effectiveness to commercial products in mice, while minimizing skin irritation often seen with standard minoxidil solutions.

This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.

This study found that freeze-dried finasteride nanoparticles improved the stability, solubility, and in vitro dissolution of the drug, indicating potential benefits for poorly water-soluble drugs.