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research Heterotypic cell contacts and basal lamina morphology during hair follicle development in the mouse: a light, scanning, and electron microscopic study at the site of tissue interaction

13 citations , December 1983 in “Canadian journal of zoology”

This study found that mesenchymal cell processes from the dermal papilla contact epithelial hair matrix cells through gaps in the basal lamina during hair matrix cell differentiation in mouse vibrissa follicles.

research Quantifying extracellular vesicle heterogeneity: the effect of process conditions on protein cargo for skin therapy

7 citations , May 2025 in “Stem Cell Research & Therapy”

This review compiles EV proteomics data and reports that while MSC-derived EVs show promise in skin therapeutics, variability in protein cargo highlights the need for standardized methodologies in understanding process impacts.

research Activating the healing process: three-dimensional culture of stem cells in Matrigel for tissue repair

5 citations , May 2024 in “BMC Biotechnology”

This study found that using three-dimensional cell culture with Matrigel enhances the biological function and stemness of stem cells, leading to improved soft tissue repair and healing by activating the host microenvironment and autologous stem cells.

research Development of a portable reflectance confocal microscope and its application in the noninvasive in vivo evaluation of mesenchymal stem cell-promoted cutaneous wound healing

2 citations , December 2022 in “Bio-Design and Manufacturing”

This study demonstrates that the newly developed portable reflectance confocal microscope (PRCM) offers real-time, noninvasive monitoring of wound healing processes by visualizing skin morphology in both mice and humans.

research Integrated evaluation of umbilical cord mesenchymal stromal cell-derived extracellular vesicles across skin-related cellular and zebrafish models

September 2026 in “Frontiers in Bioengineering and Biotechnology”

This study found that human umbilical cord mesenchymal stromal cell-derived extracellular vesicles improved several skin-related processes, including reducing oxidative injury, enhancing wound repair, and modulating androgen-related responses, in various cellular and zebrafish models.

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community Why did this recent research paper from professor Tsuji lab in Japan largely go unnoticed by this sub? Isn't this discovery huge? (hair cloning)

35 upvotes 4 months ago

A recent discovery in hair cloning identified a previously unknown cell type essential for hair follicle growth, which could potentially make lab-grown hair viable if translated to humans. However, skepticism remains due to past delays and the challenges of replicating results in humans and making the process affordable.

community Stem cells for hair, does it work?

in Technology 8 upvotes 9 months ago

Stem cell treatments for hair restoration can be effective, but results vary and depend on factors like the type of stem cells used and timing of treatment. PRP and exosomes have shown some success, while costs and effectiveness differ by location, with South Korea and Turkey offering more affordable options.

community Il PP405 è molto promettente ma non è l'unico in grado di liberarci dalla iattura

3 upvotes 1 year ago

PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.

community Researchers working on ways to regenerate lost hair from stem cells identified a recipe for normal hair regeneration in the lab. “A method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future.”

263 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.

community Exosomes - do they work as results look promising?

2 upvotes 6 years ago

Exosomes are being considered for hair regrowth, with some users reporting initial improvement. One user moved on to using dutasteride and oral minoxidil with positive results.

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