Search

for
Search:

GlossaryMEK inhibitors (MEKis)

block enzymes involved in cell growth signaling pathways

MEK inhibitors, also known as MEKis or MEK1/2 inhibitors, are a class of drugs that block the activity of the MEK enzymes (MEK1 and MEK2), which are part of the MAPK/ERK signaling pathway. This pathway is crucial for cell division and survival, and its dysregulation is often implicated in various cancers. By inhibiting MEK, these drugs can help to slow down or stop the growth of cancer cells.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 818 results

research Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails

179 citations , October 2018 in “American Journal of Clinical Dermatology”

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

research Dermatologic Adverse Events from Cancer Treatments

2 citations , October 2018 in “Springer eBooks”

Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.

research When Bugs and Drugs Conspire: Driving Acneiform Skin Toxicity

1 citations , February 2020 in “The Journal of clinical investigation/The journal of clinical investigation”

Certain cancer drugs interact with skin bacteria to cause acne-like rashes.

research Cutaneous Side Effects of Modern Targeted Therapy and Immunotherapy in Patients with Dermatological Malignancies

June 2023 in “Cancers”

Modern skin cancer treatments can cause skin side effects and hair loss, affecting patients' quality of life.

research Prevention And Management Of Dermatological Toxicities Related To Anticancer Agents: ESMO Clinical Practice Guidelines

86 citations , November 2020 in “Annals of Oncology”

Early intervention and tailored management can reduce skin side effects from cancer treatments.

View more "mekis" in research →

Community Join

5 / 32 results

community Dermal incision with verteporfin

in Research/Science 4 upvotes 2 months ago

Dermal incision with verteporfin is being explored as a potential hair loss treatment by dermatologist Melissa Toyos, with promising before-and-after photos shared on social media. The conversation discusses its potential effectiveness compared to other treatments like Minoxidil, Finasteride, and RU58841.

community 6.5 month progress with Dustasteride, Topical minoxidil and microneedling.

in Progress Pictures 54 upvotes 2 years ago

Progress made in treating hair loss using Dustasteride, topical Minoxidil and microneedling.

community 148 Days Minoxidil+Finasteride Topical, Keto Shampo 2x Weekly

in Progress Pictures 53 upvotes 3 years ago

Treating hair loss with a combination of topical minoxidil and finasteride, as well as keto shampoo twice weekly; other treatments such as microneedling and oral finasteride were discussed but the user is hesitant due to potential scarring. Additionally, another user suggested switching to oral minoxidil for further gains.

community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community New study shows that microneedling is an ineffective hair loss treatment

in Research/Science 2 years ago

The effectiveness of microneedling as a hair loss treatment, with evidence from studies and anecdotal accounts from other users. It is suggested that combining microneedling with minoxidil or finasteride may be more effective than using microneedling alone, although some people have had success using only microneedling.

View more "mekis" in community →