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This study found that cooling combined with antioxidants can improve scalp cooling effectiveness in preventing chemotherapy-induced alopecia by maintaining hair follicle viability and function.

In this study, XMU-MP-1 unexpectedly reduced cell proliferation and altered cell cycle progression in a model human hair follicle, possibly due to off-target kinase inhibition.

This study reported that Moracin M, a compound from the Moraceae family, significantly promoted hair growth and vascular regeneration by enhancing cell proliferation and Wnt signaling activation in laboratory settings, suggesting it may offer a promising alternative to existing hair growth treatments like minoxidil.

This study found that the CDK4/6 inhibitor palbociclib may protect human hair follicles from the damaging effects of taxane chemotherapy by inducing G1 arrest in stem/progenitor cells.

This study found that scalp cooling markedly reduces cellular uptake of anthracycline drugs in human keratinocytes, partially explaining its protective effect against chemotherapy-induced cytotoxicity.