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research Expression of μ-Opiate Receptor in Human Epidermis and Keratinocytes

111 citations , August 1998 in “Journal of Investigative Dermatology”

This study found that human epidermal keratinocytes express a functional μ-opiate receptor at both the mRNA and protein levels, potentially playing a role in skin physiology and pathology.

research Hair Growth Promotion by δ-Opioid Receptor Activation

1 citations , June 2021 in “Biomolecules & Therapeutics”

In this study, researchers found that activating the delta opioid receptor with a specific agonist significantly promoted hair growth in mice, suggesting potential for developing new hair-loss treatments.

research Impact of Reducing Obesity in PCOS: Methods and Treatment Outcomes

1 citations , October 2025 in “Journal of Personalized Medicine”

This review discusses various weight loss treatment options for managing PCOS in women, including lifestyle changes, diet, medications, and surgery, but reports no new clinical results.

research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells

77 citations , December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that human skin expresses proenkephalin, whose expression is upregulated by environmental stress and varies in pathological conditions, increasing in psoriasis and decreasing in melanocytic tumors.

research Eph Receptors and Ephrins: Therapeutic Opportunities

222 citations , October 2014 in “Annual Review of Pharmacology and Toxicology”

This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.

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community Quitting kratom stopped my hairloss by 80%

in Research/Science 67 upvotes 2 years ago

Quitting kratom reduced hair loss by 80% for a 23-year-old male. Others discussed kratom's effects and potential side effects on hair health.

community Trying to understand finasteride side effects and post finasteride syndrome

70 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 3 years ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

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